Capacitive Transimpedance Amplifier for Ion Mobility Spectrometers

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Solution Overview

Problem

Ion mobility spectrometers face challenges in accurately detecting and identifying ions due to low ion current signals, which require amplification and precise timing measurements, while existing amplification circuits have limitations in dynamic range and noise reduction.

Innovation Solution

The implementation of an integrated capacitive detector with a capacitive transimpedance amplifier circuit, including a feedback capacitor and offset circuit, which amplifies ion current signals and extends the dynamic range by resetting and offsetting the capacitor to manage signal limits, thereby enhancing detection accuracy and reducing noise.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a transimpedance amplifier is used to amplify low ion current signals, then detection sensitivity is improved, but the dynamic range is limited and noise increases

Engineering Contradiction:
Improvedetection sensitivityVSAvoiddynamic range
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

The patent applies dynamic resetting of the feedback capacitor to extend the dynamic range. The capacitor is periodically discharged to reset its voltage, allowing the amplifier to handle both very small and larger ion current signals without saturation. This dynamic adjustment enables the system to adapt to varying signal magnitudes while maintaining high detection sensitivity through the transimpedance amplification mechanism.

Inventive Principle:
Principle #15Dynamics

2Measurement precision

If amplification is increased to detect low ion currents, then detection accuracy is improved, but thermal noise is amplified along with the signal

Engineering Contradiction:
Improvedetection accuracyVSAvoidthermal noise
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent uses a feedback capacitor in the transimpedance amplifier configuration to convert input current signals into output voltage signals. The feedback mechanism provides stable gain determination based on the capacitor's known capacitance value, improving detection accuracy. Additionally, the periodic resetting of the feedback capacitor prevents noise accumulation and allows for controlled noise management while maintaining high amplification for low-level ion current detection.

Inventive Principle:
Principle #23Feedback

3Power

If the feedback capacitor accumulates charge to amplify signals, then signal amplification is improved, but the capacitor reaches voltage limits and requires resetting

Engineering Contradiction:
Improvesignal amplificationVSAvoidcapacitor operation duration
Core Design Contradiction:
PowerVSDuration of action of stationary object

Solution Approach 1:

The patent implements periodic resetting of the feedback capacitor through a reset switch that periodically discharges the capacitor to ground. This periodic action allows the capacitor to accumulate charge for signal amplification during each cycle, then reset to prevent voltage saturation. The periodic resetting extends the operational duration of the amplifier by enabling continuous operation across multiple signal cycles without permanent voltage limit issues.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution effectively amplifies low ion current signals, improves detection accuracy, and expands the dynamic range of the spectrometer, allowing for more precise identification of ions and reducing thermal noise, thereby enhancing the overall performance of ion mobility spectrometry.

Implementation Method 1

The CTIA comprises a feedback capacitor and an offset bias voltage is applied to a positive input of the CTIA

Methodology Applied
Scientific EffectCapacitive transimpedance amplification: Capacitance

Implementation Method 2

an offset bias voltage is applied to a positive input of the CTIA

Methodology Applied
Scientific EffectOffset bias voltage: Electric Field

Implementation Method 3

The ionized molecules drift to the opposite end of the cell at a speed dependent on the size of the ion to a collector, which causes a current pulse in the collector

Methodology Applied
Scientific EffectIon collection current: Conduction (electrical)

Implementation Method 4

Molecules in the sample of air are ionized, such as by means of a radioactive source, an ultraviolet ("UV") source, or by corona discharge

Methodology Applied
Scientific EffectIonization: Ionisation

Implementation Method 5

The cell operates at or near atmospheric pressure and contains electrodes energized to produce a voltage gradient along the cell

Methodology Applied
Scientific EffectElectrophoresis: Electrophoresis

Data Source

PatentEP2856139B1Spectrometer comprising capacitive transimpedance amplifier with offset
Publication Date: 2020.01.15 SMITHS DETECTION WATFORD LTD
  • EP2856139B1 patent drawingFigure 1
  • EP2856139B1 patent drawingFigure 2
  • EP2856139B1 patent drawingFigure 3~4

AI summary

Spectrometers including integrated capacitive detectors are described. An integrated capacitive detector integrates ion current from the collector into a changing voltage. The detector includes a collector configured to receive ions in the spectrometer, a dielectric, and a plate arranged in an overlapping configuration with collector on an opposite side of the dielectric. The detector also includes an amplifier. A capacitive detector with offset is described.