Capillary Die Fluid Transfer Device for Minute Volume Precision

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Solution Overview

Problem

High-throughput research applications face limitations in transferring precise, minute volumes of fluid due to the need for dilution to manage within existing sample transfer technologies, which can lead to contamination and waste.

Innovation Solution

A fluid transfer device utilizing a die configured to wick samples via capillary forces, combined with inkjet dispensing technology, enables controlled and precise transfer of minute volumes without mechanical actuation, reducing waste and contamination.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional sample transfer technologies are used to transfer minute volumes of fluid, then the transfer can be performed with existing equipment, but the precision and accuracy are limited and dilution is required

Engineering Contradiction:
Improveprecision of minute volume transferVSAvoidcomplexity of transfer system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces conventional mechanical pipetting systems with a capillary-based passive transport system. The capillary array device uses capillary forces to automatically draw and transport fluid samples, eliminating the need for mechanical actuation and complex positioning systems, thereby achieving high precision in minute volume transfers without increasing device complexity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent employs capillary structures with controlled porosity and surface properties to enable precise fluid uptake and transport. The capillary channels are designed with specific dimensions and surface treatments that control fluid flow through capillary action, allowing accurate transfer of minute volumes without requiring complex mechanical control systems

Inventive Principle:
Principle #31Porous materials

2Ease of operation

If fluid is diluted to a larger volume to make it manageable with existing technologies, then the fluid becomes easier to handle, but waste and contamination increase

Engineering Contradiction:
Improveease of handling fluidVSAvoidwaste and contamination
Core Design Contradiction:
Ease of operationVSLoss of substance

Solution Approach 1:

The capillary array device is designed to be self-filling through capillary action, automatically drawing the required fluid volumes without external intervention or dilution. The device handles minute volumes directly in their concentrated form, eliminating the need for dilution steps and thereby reducing waste and contamination while maintaining ease of operation

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the operational parameters of fluid handling by operating in the minute volume regime directly rather than diluting to larger volumes. The capillary dimensions, surface energies, and flow rates are optimized for handling small volumes, enabling easy operation without dilution and thus minimizing substance loss

Inventive Principle:
Principle #35Parameter changes

3Reliability

If conventional mechanical actuation is used for fluid transfer, then the transfer process is well-established, but contamination and waste are increased

Engineering Contradiction:
Improvereliability of transfer processVSAvoidcontamination and waste
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent replaces mechanical actuation systems with a passive capillary-based system that relies on surface tension and capillary forces for fluid transport. This eliminates mechanical contact points that could introduce contamination, while the sealed capillary structure prevents external contamination, thereby maintaining reliability while reducing harmful factors

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The capillary channels act as intermediaries between the fluid source and destination, providing a controlled environment for fluid transport. The capillary walls serve as a barrier that prevents contamination from the external environment, while the capillary forces ensure reliable fluid movement without mechanical intervention, reducing both contamination and waste

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise and controlled transfer of fluid volumes ranging from 1 picoliter to 10 microliters with reduced waste and contamination, allowing for single or multiple transfers and easy cleaning of the device.

Implementation Method 1

a die configured to wick the sample fluid and maintain the sample fluid via capillary forces

Methodology Applied
Scientific EffectCapillary forces: Capillary Action

Data Source

PatentUS8658110B2Fluid delivery system
Publication Date: 2014.02.25 HEWLETT PACKARD DEVELOPMENT COMPANY LP
  • US8658110B2 patent drawing
  • US8658110B2 patent drawing
  • US8658110B2 patent drawing

AI summary

Embodiments of a fluid delivery system are disclosed.