Capillary Gas Enrichment via Intersecting Stream Collision

Solution Overview

Problem

Conventional methods for enriching liquids with high concentrations of dissolved gas, such as oxygen, often result in bubble formation and require complex extracorporeal circuits, which are costly, difficult to operate, and can lead to inflammatory reactions and coagulation issues.

Innovation Solution

A system using two or more capillaries positioned at an intersecting angle within a conduit to deliver gas-enriched liquid, ensuring localized convective mixing without exposure to boundary surfaces, thereby preventing bubble formation and achieving homogeneous gas distribution within the liquid.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If gas-supersaturated liquid is delivered at ambient pressure, then gas concentration in liquid is improved, but gas bubbles form

Engineering Contradiction:
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The liquid flow is divided into multiple streams by positioning multiple capillaries at intersecting angles. Each capillary delivers gas-supersaturated liquid that collides with other streams, creating localized mixing zones that prevent bubble formation while maintaining high gas concentration.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The capillaries are positioned at intersecting angles (e.g., 90 degrees) to each other, creating a three-dimensional mixing pattern. This angular arrangement causes liquid streams to collide and mix in a manner that dissipates gas supersaturation before bubbles can form, adding a spatial dimension to the mixing process.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Quantity of substance

If conventional oxygenators are used in extracorporeal circuits, then blood oxygenation is achieved, but device complexity and operational difficulty increase

Engineering Contradiction:
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The invention extracts the oxygenation function from the complex extracorporeal circuit and implements it directly within the blood vessel using simple capillaries. This removes the need for external oxygenators, pumps, and large-volume circuits, leaving only the essential function of delivering oxygen-enriched liquid.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system uses the patient's own blood flow as the mixing medium. The gas-supersaturated liquid delivered through capillaries mixes automatically with the flowing blood in the vessel, eliminating the need for external pumps or complex circulation systems.

Inventive Principle:
Principle #25Self-service

3Quantity of substance

If gas-supersaturated liquid is injected directly into blood, then oxygen enrichment is achieved, but gaseous embolism risk increases

Engineering Contradiction:
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The system performs preliminary mixing of the gas-supersaturated liquid with blood flow before the mixture reaches areas where bubbles could cause embolism. By injecting through multiple capillaries positioned at angles, the liquid is pre-mixed and de-saturated in controlled zones within the vessel, preventing subsequent bubble formation.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The flowing blood acts as an intermediary medium that receives and distributes the gas-supersaturated liquid from the capillaries. The blood flow carries the enriched liquid away from the injection site, preventing localized supersaturation that would lead to bubble formation and embolism.

Inventive Principle:
Principle #24Intermediary (Mediator)

4Productivity

If conventional oxygenators with large blood contact surface area are used, then oxygenation efficiency is improved, but inflammatory reaction and coagulation risk increase

Engineering Contradiction:
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

Instead of using a large surface area oxygenator that contacts blood throughout, the invention concentrates oxygenation at localized points where capillaries inject gas-enriched liquid. This localized approach achieves oxygenation without the extensive blood-surface contact that triggers inflammation and coagulation.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for efficient gas enrichment of liquids, such as blood, without bubble formation, simplifying the process by eliminating the need for extracorporeal mixing and reducing the risk of inflammatory reactions and coagulation, while achieving hyperbaric oxygen levels.

Implementation Method 1

the first ends of the capillaries form an intersecting angle with respect to the effluent streams such that these streams of gas-enriched liquid collide with each other upon exit from the first ends of the capillaries, effecting localized convective mixing within the larger liquid conduit

Methodology Applied
Scientific EffectConvective mixing: Convection

Data Source

PatentUS20250099923A1Method for Bubble-Free Gas-Enrichment of a Flowing Liquid within a Conduit
Publication Date: 2025.03.27
  • US20250099923A1 patent drawing
  • US20250099923A1 patent drawing
  • US20250099923A1 patent drawing

AI summary

The present invention provides a system for enriching a flowing liquid with a dissolved gas inside a conduit. The system comprises two or more capillaries, each capillary delivering a stream of a gas-enriched liquid to the flowing liquid. The first ends of the capillaries are positioned to form an intersecting angle with respect to the effluent streams such that these streams of gas-enriched liquid collide with each other upon exit from the first ends of the capillaries, effecting localized convective mixing within the larger liquid conduit before these gas-enriched streams are able to come into close contact with the boundary surfaces of the conduit, whereby the gas-enriched liquid mixes with the flowing liquid to form a gas-enriched flowing liquid. In the preferred embodiment, no observable bubbles are formed in the gas-enriched flowing liquid. Methods of making and using such system are also provided.