Capillary Electrophoresis Optical Self-Diagnosis Using Absolute Image Values
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Solution Overview
Problem
Existing capillary electrophoresis devices require manual operations by a service engineer to check optical performance after shipment, which is inefficient and prone to inaccuracies due to the use of relative indices.
Innovation Solution
A capillary electrophoresis device equipped with a control unit that automatically diagnoses optical performance by comparing absolute values from an image captured by a detecting unit with predetermined reference values, eliminating the need for manual operations.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If manual operation by service engineer is used to check optical performance, then optical performance can be checked, but the process is inefficient and requires special work
Solution Approach 1:
The capillary electrophoresis device performs self-diagnosis of its optical system by automatically capturing images with the detection unit, extracting absolute values from the images, and comparing them with reference values to determine optical performance, eliminating the need for manual service engineer intervention
Solution Approach 2:
The patent replaces manual mechanical inspection with an automated optical measurement system that uses the detection unit to capture images and the control unit to automatically process and analyze the optical performance data
2Measurement precision
If relative index is used for optical performance measurement, then measurement can be performed, but accuracy is reduced
Solution Approach 1:
The patent changes the measurement parameter from relative index to absolute value, where the control unit extracts absolute values directly from images captured by the detection unit and compares them with reference absolute values, thereby improving measurement accuracy and reliability
3Productivity
If automated diagnosis is implemented, then operational efficiency is improved, but device complexity increases
Solution Approach 1:
The control unit and detection unit are designed to serve multiple functions: they are used both for normal capillary electrophoresis operation and for automated optical performance diagnosis, eliminating the need for separate dedicated diagnostic hardware and reducing overall system complexity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate and automated optical performance diagnosis without manual intervention, ensuring precise alignment and adjustment of optical components.
Implementation Method 1
a light source that causes laser light to oscillate
Implementation Method 2
a detecting unit that detects light emitted when the capillary array is irradiated with the laser light
Data Source
AI summary
An object of the present invention is to provide a capillary electrophoresis device and an optical performance diagnostic method for the same that are capable of checking optical performance without performing special work. Therefore, according to the present invention, the capillary electrophoresis device includes a capillary array including a plurality of capillaries, a light source that causes laser light to oscillate, a detecting unit that detects light emitted when the capillary array is irradiated with the laser light, and a control unit that performs predetermined processing based on a signal from the detecting unit. The control unit extracts a predetermined absolute value regarding an optical index based on an image captured by the detecting unit, and calculates the optical index by comparing the extracted absolute value with a predetermined reference value.


