Capillary Pipetting Device for Hemolysis-Free Blood Transfer
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Solution Overview
Problem
Existing methods for withdrawing, transporting, and dispensing blood face challenges such as blood becoming viscous due to hemolysis when exposed to environment conditions or surfaces, leading to inefficiencies and inconsistencies.
Innovation Solution
A capillary pipetting device comprising a pipette with a bulb portion and an end portion, where the end portion includes an insertion portion and a capillary tube positioned within and extending beyond the insertion portion, allowing for efficient blood transfer and dispensing.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional blood withdrawal methods are used, then blood can be withdrawn from vessels, but blood becomes viscous due to hemolysis when exposed to environment conditions or surfaces
Solution Approach 1:
The patent introduces a closed system with a pipette and microcentrifuge tube as intermediaries between the blood vessel and the external environment. The capillary tube serves as a mediator to transport blood without direct exposure to environmental surfaces, preventing hemolysis while maintaining blood fluidity throughout the withdrawal and transfer process
Solution Approach 2:
The invention extracts the blood sample directly from the vessel into a sealed capillary tube, removing the blood from the vulnerable environment quickly and transferring it to a protected container. This extraction method minimizes the time blood is exposed to potential hemolytic conditions while maintaining sample integrity
2Productivity
If conventional blood transfer methods are used, then blood can be transferred to containers, but the process is inefficient and inconsistent
Solution Approach 1:
The capillary tube utilizes capillary action to automatically draw and transfer blood without requiring external suction devices or complex mechanical systems. The narrow capillary tube dimensions and material properties enable self-driven blood transfer, improving efficiency while maintaining consistent dispensing volumes through controlled capillary forces
Solution Approach 2:
The patent replaces conventional mechanical suction systems with capillary action-driven transfer. The capillary tube's physical properties (diameter, material) create a passive mechanical system that consistently delivers precise blood volumes without requiring external pressure sources or complex dispensing mechanisms
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device enables swift, reliable, and consistent withdrawal, transportation, and dispensing of blood, minimizing hemolysis and maintaining blood fluidity, thus improving precision and consistency in blood handling.
Implementation Method 1
A capillary pipetting device comprising a pipette with a bulb portion and an end portion, where the end portion includes an insertion portion and a capillary tube positioned within and extending beyond the insertion portion, allowing for efficient blood transfer
Implementation Method 2
compressing, via the compressible wall, at least one of the bulb portion and the reservoir portion of the pipette, thereby transferring blood from the capillary tube to the container
Data Source
AI summary
A blood transfer device is disclosed. The blood transfer device includes a pipette comprising a bulb portion, wherein the bulb portion comprises a compressible wall and an aperture extending through the compressible wall and an end portion opposite the bulb portion, wherein the end portion comprises an insertion portion, and wherein the end portion is in fluid communication with the bulb portion. The blood transfer device further includes a capillary tube, wherein the capillary tube is positioned at least partially within the end portion and extends at least partially beyond the insertion portion.