Capillary Scanning Unit for Precise Optical Sample Detection
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing scanning detectors for capillary isoelectric focusing lack specific configurations for simple and accurate sample detection, and capillary connections in analytical techniques like capillary electrophoresis and HPLC are cumbersome, especially for short functional capillaries.
Innovation Solution
A scanning unit with an optical system and restriction unit that restricts the capillary in a predetermined position, allowing for precise sample detection, and a microcolumn connector for compact capillary connections.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multiple members (sleeve member, ferrule member, set screw) are used to connect capillaries, then the connection is liquid-tight and reliable, but the connecting portion occupies a large volume and increases device complexity
Solution Approach 1:
The patent merges multiple connection members (sleeve member, ferrule member, set screw) into a single integrated connector. The connector includes an outer diameter expansion portion that integrates the functions of the sleeve member and ferrule member, and a fastening portion that integrates the set screw function, thereby reducing the number of parts and connecting volume while maintaining connection reliability
Solution Approach 2:
The connector is designed with multi-functionality to perform multiple operations: the outer diameter expansion portion expands the capillary outer diameter and provides structural support, the fastening portion secures the capillary with a set screw, and the connector enables both mechanical attachment and liquid-tight sealing through its integrated structure
2Stability of the object's composition
If a plurality of members is attached to the connecting part, then the connection structure is stable, but a certain length is required for the capillary to attach these members, making very short functional capillaries difficult to connect
Solution Approach 1:
The patent combines multiple connection functions into a single compact connector that requires minimal capillary length. The integrated structure eliminates the need for multiple separate members that would each require attachment space, enabling connection of very short functional capillaries while maintaining connection stability
3Volume of stationary object
If the detector is moved with respect to a fixed capillary, then space restrictions are accommodated and the device is more compact, but the detection system becomes more complex
Solution Approach 1:
The patent introduces a scanning unit as an intermediary component that moves along the capillary axis to perform detection. This scanning unit includes a light source, optical system, and photodetector arranged in a compact configuration, enabling detector movement while maintaining system compactness and managing complexity through functional integration
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables simple and highly accurate sample detection in capillaries, facilitating compact connections and fine flow control in capillary systems.
Implementation Method 1
the first optical system having one or more optical elements that transmits light along the first optical axis to the appropriate position; and the second optical system having one or more optical elements that transmits emitted light from the appropriate position along the second optical axis
Data Source
AI summary
The present disclosure is to provide a scanning unit that enables simple and highly accurate detection of a sample in a capillary. A scanning unit according to the present disclosure is a scanning unit that moves in the axial direction of a capillary and includes an optical system unit having an optical system and a restriction unit that restricts the capillary to a predetermined position. The optical system unit includes a first optical system having one or more optical elements that transmits incident-side light to a predetermined position along a first optical axis; and a second optical system having one or more optical elements transmitting output light along a second optical axes.