Compact Drug Delivery Drive Assembly With Capstan And Tether

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Solution Overview

Problem

Existing drug delivery devices have large footprints due to complex drive assemblies, which increase size and manufacturing costs, and are not suitable for wearable injectors that require a compact design.

Innovation Solution

A drive assembly with a capstan and tether system that allows for a compact design by laterally offsetting the rotational axis of the capstan from the stopper's longitudinal axis, using a tether to regulate the expansion of the stopper biasing member, and incorporating a guide surface for tether direction change, along with a lock member for assembly ease.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a complex drive assembly with multiple components and mechanisms is used to control motion direction and speed, then the drug delivery functionality is improved, but the device footprint and overall size increase

Engineering Contradiction:
Improvedrug delivery functionalityVSAvoiddevice footprint
Core Design Contradiction:
Adaptability or versatilityVSArea of stationary object

Solution Approach 1:

The patent combines the capstan, tether, and biasing member into an integrated drive assembly that provides both motion control and drug expulsion functionality. The capstan rotates to wind and unwind the tether, which directly controls the biasing member's expansion and contraction, eliminating the need for separate control mechanisms and reducing overall device size while maintaining full drug delivery capability

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The drive assembly components are nested within each other to minimize footprint. The tether is wound around the capstan, which is positioned within the drive housing, and the biasing member is contained within the same housing. This nested arrangement allows all functional components to occupy minimal space while maintaining their operational independence and effectiveness

Inventive Principle:
Principle #7Nested doll (Nesting)

2Adaptability or versatility

If a complex drive assembly with multiple components is used, then the drug delivery functionality is improved, but the manufacturing cost and assembly time increase

Engineering Contradiction:
Improvedrug delivery functionalityVSAvoidassembly complexity
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The drive assembly is segmented into distinct functional components (capstan, tether, biasing member, drive housing) that can be manufactured separately using standard processes and then assembled through simple, well-defined operations. This segmentation allows each component to be optimized for its specific function while simplifying the overall assembly process, reducing both manufacturing cost and assembly time compared to integrated complex mechanisms

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The capstan serves multiple functions: it winds and unwinds the tether to control the biasing member's expansion, provides a mechanical advantage for force multiplication, and acts as a compact motion control element. This multi-functionality reduces the total number of components needed, simplifying assembly while maintaining comprehensive drug delivery functionality

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Area of stationary object

If the capstan rotational axis is laterally offset from the stopper longitudinal axis, then the device size is reduced, but the tether routing complexity increases

Engineering Contradiction:
Improvedevice sizeVSAvoidtether routing
Core Design Contradiction:
Area of stationary objectVSDevice complexity

Solution Approach 1:

The lateral offset of the capstan rotational axis from the stopper longitudinal axis creates a three-dimensional tether routing path that allows the tether to wrap around the capstan in a compact configuration. This dimensional arrangement enables the tether to efficiently transmit force while accommodating the offset geometry, reducing overall device size without requiring complex additional routing components

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution reduces the overall size of the drug delivery device, simplifies assembly, and lowers manufacturing costs while maintaining effective drug expulsion functionality.

Implementation Method 1

the stopper biasing member is configured to expand to move the stopper through the reservoir when released from the energized state

Methodology Applied
Scientific EffectElastic expansion: Elasticity

Implementation Method 2

The tether is pulled taut against the guide surface of the drive housing by the stopper biasing member

Methodology Applied
Scientific EffectFriction: Friction

Data Source

PatentEP3694578B1Drug delivery device with drive assembly and related method of assembly
Publication Date: 2025.09.24 AMGEN INC
  • EP3694578B1 patent drawingFigure 1~2
  • EP3694578B1 patent drawingFigure 3
  • EP3694578B1 patent drawingFigure 4~5

AI summary

Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a main housing having an exterior surface releasably attachable to a patient, a container disposed in an enclosed space defined by an interior surface of the main housing, and a drive assembly. The container may include a reservoir containing a drug and a stopper. The drive assembly may include drive housing and a tether which slidably engages and is pulled taut against a guide surface of the drive housing. A first end of the tether may be wound around a capstan which is mounted rotatably relative to the drive housing. A second end of the tether may be operably connected to a stopper biasing member. The tether may initially retain the stopper biasing member in an energized state. When released, the stopper biasing member may expand to move the stopper through the reservoir.