Capsule Light Source for Photoimmunotherapy

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Solution Overview

Problem

Near-infrared light with a specific wavelength used in photoimmunotherapy struggles to effectively reach affected areas, such as cancer tissue, due to tissue absorption, particularly thick fat under the skin, limiting treatment efficacy.

Innovation Solution

A light emitting type capsule treatment tool is developed, comprising a power receiving coil, a magnetic member, and a light emitting member housed in a capsule, which can be powered via electromagnetic induction to emit light at a specific wavelength, allowing for closer irradiation of affected areas within the body.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Illumination intensity

If near-infrared light is irradiated from outside the body, then treatment can be performed with light having certain permeability to tissue, but the light cannot effectively reach affected areas covered with thick fat under the skin

Engineering Contradiction:
Improvelight penetration depthVSAvoidtissue absorption
Core Design Contradiction:
Illumination intensityVSObject-affected harmful factors

Solution Approach 1:

The patent inverts the conventional approach by placing the light source inside the body rather than outside. The capsule-shaped treatment tool is introduced into the body cavity or tissue, and the light emitting member irradiates near-infrared light directly at the affected area from within, eliminating the barrier of thick subcutaneous fat that blocks external light penetration.

Inventive Principle:
Principle #13The other way round (Inversion)

Solution Approach 2:

The capsule-shaped treatment tool serves as an intermediary carrier that delivers the light emitting member to the target site. The capsule housing protects the power receiving coil and light emitting member while enabling minimally invasive introduction into the body, and the light itself acts as an intermediary energy carrier to activate photosensitive substances at the affected area.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Illumination intensity

If a capsule-shaped treatment tool with power receiving coil and light emitting member is introduced into the body, then light can be irradiated from a closer position to affected areas, but the device requires wireless power supply through electromagnetic induction

Engineering Contradiction:
Improvelight irradiation effectivenessVSAvoidwireless power supply system
Core Design Contradiction:
Illumination intensityVSDevice complexity

Solution Approach 1:

The patent replaces the conventional mechanical wire-based power supply system with a wireless electromagnetic induction system. The power receiving coil in the capsule interacts with an external transmission antenna through magnetic coupling, eliminating the need for physical connections and reducing mechanical complexity while enabling flexible positioning of the light source at the target site.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of operation

If the treatment tool is made as a small capsule to be easily placed at treatment points, then the device can be introduced via endoscope, medical tube, or needle, but the capsule must house power receiving coil, magnetic member, and light emitting member

Engineering Contradiction:
Improveintroduction methodVSAvoidcapsule housing volume
Core Design Contradiction:
Ease of operationVSVolume of stationary object

Solution Approach 1:

The patent applies nesting by placing the light emitting member inside the capsule housing that also contains the power receiving coil and magnetic member. The components are arranged concentrically or in nested configurations to maximize space utilization, allowing all necessary functional elements to be contained within a small capsule volume suitable for minimally invasive introduction.

Inventive Principle:
Principle #7Nested doll (Nesting)

Solution Approach 2:

The capsule housing serves as a flexible or semi-rigid shell that protects the internal components while maintaining a compact size. The housing material and结构设计 allow the capsule to be sufficiently small for introduction via endoscope, medical tube, or needle, yet robust enough to contain and protect the power receiving coil, magnetic member, and light emitting member during insertion and operation.

Inventive Principle:
Principle #30Flexible shells and thin films

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The tool enables effective irradiation of light at a specific wavelength on cancer tissue from a closer position, enhancing treatment efficacy by overcoming tissue absorption issues, and can be easily placed using endoscopes, medical tubes, or needles, or swallowed for internal application.

Implementation Method 1

a power receiving coil formed by winding a conductive wire and configured to receive electric power supplied from an external transmission antenna via a magnetic flux

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Data Source

PatentUS11160992B2Light-emitting capsule treatment tool
Publication Date: 2021.11.02 PIOLAX INC
  • US11160992B2 patent drawing
  • US11160992B2 patent drawing
  • US11160992B2 patent drawing

AI summary

A light emitting type capsule treatment tool for irradiating light with a specific wavelength required for photoimmunotherapy, includes a power receiving coil, a magnetic member, a light emitting member and a capsule. The power receiving coil is formed by winding a conductive wire and configured to receive electric power supplied from an external transmission antenna via a magnetic flux. The magnetic member is placed on an inner circumference of the power receiving coil. The light emitting member is configured to be supplied with electric power from the power receiving coil and to emit the light with the specific wavelength. The capsule houses the power receiving coil, the magnetic member and the light emitting member.