Automated Capsulorhexis Incision via OCT Imaging and Laser Ablation

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Solution Overview

Problem

Current ophthalmic surgical techniques face challenges in accurately and reliably performing capsulotomy and other ocular incisions due to issues like inadequate visualization, parallax errors, and difficulties with soft and elastic capsules, which can lead to complications during intraocular lens implantation.

Innovation Solution

A method and system utilizing an optical beam scanning system with OCT imaging to accurately align and perform capsulorhexis incisions, allowing for precise 3D scanning and plasma-mediated ablation, enabling the creation of precise ocular incisions regardless of capsule stiffness or orientation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual capsulorhexis technique is used, then surgeon flexibility is maintained, but incision accuracy and reliability deteriorate due to visualization issues and parallax errors

Engineering Contradiction:
Improveincision accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces manual mechanical capsulorhexis techniques with an automated laser-based system. The laser system uses optical coherence tomography (OCT) imaging to visualize the capsule and automatically performs capsulorhexis incisions, eliminating the need for manual mechanical manipulation and improving incision accuracy while reducing parallax errors associated with stereoscopic imaging.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent uses OCT imaging to create a detailed optical copy or map of the capsule structure before performing the incision. This pre-operative imaging allows the system to plan and execute the capsulorhexis with high precision by referencing the captured 3D structural information, thereby improving measurement precision without requiring complex real-time mechanical adjustments.

Inventive Principle:
Principle #26Copying

2Manufacturing precision

If automated laser system is used, then incision precision is improved, but visualization requirements increase

Engineering Contradiction:
Improveincision precisionVSAvoidcapsule visualization
Core Design Contradiction:
Manufacturing precisionVSDifficulty of detecting and measuring

Solution Approach 1:

The patent replaces traditional optical visualization methods with OCT imaging technology. OCT uses low-coherence interferometry to generate cross-sectional images of the capsule, providing high-resolution structural information without relying on optical transparency or red reflex, thereby enabling precise automated laser incisions even in challenging visualization conditions.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent transitions from 2D surface visualization to 3D volumetric imaging using OCT. This dimensional enhancement allows the system to visualize the capsule structure in cross-section and plan the capsulorhexis incision path in three dimensions, improving incision precision by providing comprehensive structural information that is not available with traditional 2D imaging methods.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system enhances the accuracy and reliability of ocular incisions, improving the safety and efficiency of intraocular lens implantation by providing clear visualization and precise control over the cutting process, reducing complications related to capsule stiffness and orientation.

Implementation Method 1

A method and system utilizing an optical beam scanning system with OCT imaging to accurately align and perform capsulorhexis incisions

Methodology Applied
Scientific EffectOptical coherence tomography: Tomography

Implementation Method 2

allowing for precise 3D scanning and plasma-mediated ablation

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 3

allowing for precise 3D scanning and plasma-mediated ablation

Methodology Applied
Scientific EffectPlasma: Plasma

Data Source

PatentEP3138475B1Apparatus for automated placement of scanned laser capsulorhexis incisions
Publication Date: 2023.10.25 AMO DEVELOPMENT LLC
  • EP3138475B1 patent drawingFigure 1
  • EP3138475B1 patent drawingFigure 2
  • EP3138475B1 patent drawingFigure 3

AI summary

Systems and methods are described for cataract intervention. In one embodiment a system comprises a laser source configured to produce a treatment beam comprising a plurality of laser pulses; an integrated optical system comprising an imaging assembly operatively coupled to a treatment laser delivery assembly such that they share at least one common optical element, the integrated optical system being configured to acquire image information pertinent to one or more targeted tissue structures and direct the treatment beam in a 3-dimensional pattern to cause breakdown in at least one of the targeted tissue structures; and a controller operatively coupled to the laser source and integrated optical system, and configured to adjust the laser beam and treatment pattern based upon the image information, and distinguish two or more anatomical structures of the eye based at least in part upon a robust least squares fit analysis of the image information.