Carboxamide Pesticidal Mixtures for Synergistic Pest Control
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Solution Overview
Problem
Current pest control methods face challenges in reducing dosage rates to minimize environmental and toxicological effects, achieving broad-spectrum efficacy, combining rapid and long-lasting action, and preventing pest resistance development.
Innovation Solution
The use of pesticidal mixtures comprising a carboxamide compound and other active compounds such as acetylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acetylcholine receptor agonists, and microbial disruptors, applied singly or in combination to enhance pest control efficacy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If dosage rates of active ingredient are reduced to minimize environmental and toxicological effects, then environmental safety is improved, but pest control efficacy deteriorates
Solution Approach 1:
The patent combines multiple pesticidal compounds with different modes of action (carboxamide compound I plus compound II from group M) into synergistic mixtures. This merging allows reduced dosage rates of each individual compound while maintaining or enhancing overall pest control efficacy, thereby reducing environmental and toxicological effects without sacrificing control reliability.
Solution Approach 2:
The invention creates composite pesticidal formulations comprising carboxamide compound I in combination with compound II from group M (such as AChE inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, etc.). These composite materials exhibit synergistic effects, enabling effective pest control at lower dosage rates and thus minimizing environmental harm.
2Ease of operation
If repeated and exclusive application of an individual pesticidal compound is used, then application simplicity is improved, but pest resistance development accelerates
Solution Approach 1:
The patent merges compounds with different modes of action (carboxamide compound I and compound II from group M) into single formulations. This combination approach maintains ease of application while preventing resistance development, as pests cannot easily develop resistance to multiple different modes of action simultaneously.
Solution Approach 2:
The invention changes the parameter of mode of action diversity by combining compounds that act through different mechanisms (carboxamide compound I plus compound II from group M including AChE inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acetylcholine receptor agonists, and microbial disruptors). This parameter change effectively prevents resistance while maintaining application simplicity.
3Adaptability or versatility
If broad-spectrum pest control is achieved through multiple compounds, then spectrum of activity is improved, but formulation complexity increases
Solution Approach 1:
The patent combines carboxamide compound I with compound II from group M (which includes diverse classes such as carbamates, organophosphates, cyclodiene organochlorine compounds, fiproles, pyrethroids, neonicotinoids, spinosyns, avermectins, and microbial disruptors) to achieve broad-spectrum pest control. This merging provides versatility against multiple pest types while the formulation is designed to manage complexity through systematic combination rules.
Data Source
AI summary
The disclosure relates to pesticidal mixtures comprising as active compound I an insecticidal active carboxamide derivative and at least one active compound II selected from a group M comprising acteylcholine esterase inhibitors, GABA-gated chloride channel antagonists, sodium channel modulators, nicotinic acteylcholine receptor agonists/antagonists, allosteric nicotinic acetylcholine receptor activitaors, chloride channel activators, juvenile hormone mimics, homopteran feeding blockers, mit grow inhibitors, inhibitors of mitochondrial ATP synthase, uncouplers of the oxidative phosphorylation, inhibitors of the chitin biosynthesis, moulting disruptors, ecdyson receptor agonists, octamin receptor agonists, inhibitors of the MET, voltage-dependent sodium channel blockers, inhibitors of the lipid synthesis, ryanodine receptor modulators and other compounds as defined in the description, in synergistically effective amounts. The disclosure also relates to methods using these mixtures for combating and controlling insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially for protecting plant proparagation material, such as seeds.