Cardiac Activation Reconstruction via Divergence Criteria

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Solution Overview

Problem

Current systems fail to accurately identify and reconstruct cardiac activation information in complex heart rhythm disorders, such as atrial fibrillation, ventricular tachycardia, and ventricular fibrillation, due to overlapping electrical waves and far-field activations, making it difficult to determine the source of the disorder and target it for effective treatment.

Innovation Solution

A method that involves accessing neighboring cardiac signals, eliminating far-field activations using divergence criteria, and constructing a clinical representation of local activations to accurately determine activation onset times and identify the source of the disorder, allowing for precise targeting and treatment.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If conventional signal processing methods are used to analyze cardiac signals in complex rhythm disorders, then the analysis process is simplified, but the accuracy of identifying local activation onsets deteriorates due to overlapping electrical waves and far-field activations

Engineering Contradiction:
Improvesignal processing complexityVSAvoidactivation onset identification accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The method segments cardiac signals by comparing neighboring electrogram signals to identify points of change where local activations occur. By dividing the continuous cardiac signal into discrete activation events based on divergence criteria, the system can distinguish local activations from far-field activations and overlapping waves, improving measurement precision without requiring overly complex processing

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention introduces an intermediary computational step that compares pairs of neighboring electrogram signals to detect points of change. This intermediary process of comparing adjacent signals serves as a mediator to identify local activation onsets, enabling accurate detection even in the presence of complex overlapping electrical waves and far-field activations

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If ablation therapy is performed without accurate identification of the earliest activation location, then treatment can be delivered quickly, but the efficacy of treating complex rhythm disorders deteriorates

Engineering Contradiction:
Improvetreatment delivery speedVSAvoidtreatment efficacy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs preliminary identification of the earliest activation location and construction of a clinical representation before ablation therapy is delivered. By pre-identifying the precise target location through signal analysis and divergence criteria, the system enables rapid subsequent delivery of ablation energy to the correct site, achieving both high productivity and reliability

Inventive Principle:
Principle #10Preliminary action

3Quantity of substance

If multiple sensors are used to capture cardiac electrical activity, then more comprehensive data is obtained, but the difficulty of distinguishing local from far-field activations increases

Engineering Contradiction:
Improvecardiac signal data volumeVSAvoidlocal vs far-field activation discrimination
Core Design Contradiction:
Quantity of substanceVSDifficulty of detecting and measuring

Solution Approach 1:

The method segments and compares signals from multiple neighboring sensors to identify points of change. By systematically comparing each sensor's signal with its neighbors and applying divergence criteria, the system can distinguish local activations (which appear as points of change in multiple neighboring signals) from far-field activations, making the discrimination process more manageable despite the large quantity of data

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The invention merges information from multiple neighboring electrogram signals through comparison and analysis. By combining the data from multiple sensors and identifying consistent points of change across neighboring signals, the system enhances the ability to distinguish local from far-field activations, transforming the challenge of multiple data sources into an advantage for accurate localization

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS10271786B2System and method for reconstructing cardiac activation information
Publication Date: 2019.04.30 TOPERA INC
  • US10271786B2 patent drawing
  • US10271786B2 patent drawing
  • US10271786B2 patent drawing

AI summary

Reconstruction of cardiac information associated with a heart rhythm disorder includes accessing a plurality of neighboring cardiac signals and eliminating far-field activations from the neighboring cardiac signals using one or more divergence criteria that define local activations, where the divergence criteria is associated with divergence among the plurality of neighboring cardiac signals. The local activations in the plurality of neighboring cardiac signals may be used to construct a clinical representation of the heart rhythm disorder.