Multi-channel cardiac measurement with adaptive channel replacement

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Solution Overview

Problem

Current multi-channel cardiac electrogram (MCCE) processing algorithms provide inaccurate measurements, leading to misleading activation maps and prolonged cardiac procedures, as they are simplistic and prone to noise and variability in cardiac signals.

Innovation Solution

An automatic method for accurately measuring cardiac parameters like cycle length and local activation time, which involves selecting reference and mapping channels, monitoring signal quality, and replacing sub-standard channels to ensure reliable data, using techniques such as velocity-dependent signal generation and autocorrelation to maintain timing information accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If simplistic MCCE processing algorithms are used, then device complexity is reduced, but measurement precision deteriorates leading to inaccurate cardiac parameter measurements

Engineering Contradiction:
Improvealgorithm complexityVSAvoidcardiac parameter measurement accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The algorithm segments the MCCE signal processing into multiple distinct stages: quality assessment of individual channels, selective channel replacement, velocity-dependent signal generation, and autocorrelation-based parameter extraction. This segmentation allows each stage to be optimized independently, improving measurement precision without requiring the entire system to be overly complex.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The algorithm performs preliminary quality assessment and channel selection before the main parameter extraction process. By pre-identifying and replacing substandard channels, and pre-generating velocity-dependent signals, the main processing stage can focus on accurate measurement rather than signal validation, improving overall precision.

Inventive Principle:
Principle #10Preliminary action

2Reliability

If multiple channels are monitored and replaced when quality degrades, then reliability improves, but device complexity increases

Engineering Contradiction:
Improvesignal quality reliabilityVSAvoidchannel monitoring system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system performs self-diagnosis and self-correction by automatically assessing the quality of each MCCE channel and replacing degraded channels with alternative channels from the multi-channel array. This self-service mechanism improves reliability without requiring external intervention or overly complex manual monitoring systems.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The algorithm dynamically changes the operational parameters by switching between different channels based on their quality metrics. When a channel's signal quality deteriorates below a threshold, the system changes to a different channel's data, maintaining reliable measurements without requiring complex hardware modifications.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If velocity-dependent signal generation and autocorrelation are used, then measurement precision improves, but use of energy increases

Engineering Contradiction:
Improvetiming information accuracyVSAvoidsignal processing energy consumption
Core Design Contradiction:
Measurement precisionVSUse of energy by moving object

Solution Approach 1:

The algorithm applies velocity-dependent signal generation and autocorrelation selectively to the essential timing-critical portions of the signal rather than processing the entire signal spectrum with equal intensity. This partial action approach maintains high timing precision while reducing the total computational energy required compared to exhaustive signal processing methods.

Inventive Principle:
Principle #16Partial or excessive action

4Productivity

If rapid parameter measurement is implemented, then productivity increases, but measurement precision may deteriorate

Engineering Contradiction:
Improveprocedure speedVSAvoidcardiac parameter accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

By pre-assessing channel quality and pre-generating velocity-dependent signals before the main parameter extraction, the system eliminates time-consuming validation steps during the critical measurement phase. This preliminary preparation enables rapid parameter extraction without sacrificing precision, as the data quality is already guaranteed by the pre-screening process.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The algorithm replaces traditional mechanical or manual signal analysis methods with automated digital signal processing techniques. The use of automated autocorrelation and velocity-dependent signal generation allows rapid computation of cardiac parameters with high precision, eliminating the time-consuming manual analysis that would compromise productivity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentEP2967400B1Multi-channel cardiac measurements
Publication Date: 2019.07.24 APN HEALTH LLC
  • EP2967400B1 patent drawingFigure 1
  • EP2967400B1 patent drawingFigure 2
  • EP2967400B1 patent drawingFigure 3A~3B

AI summary

An automatic method of determining local activation time (LAT) in multi-channel cardiac electrogram signals including a plurality of cardiac channels, the method comprising: (a) storing the cardiac channel signals; (b) selecting a mapping channel, a ventricular channel, and a reference channel from among the plurality of cardiac channels; (c) using the selected channels to compute first LAT values at a plurality of mapping-channel locations; (d) monitoring the quality of at least one selected channel; (e) if the quality of a monitored cardiac channel falls below a standard, replacing the sub-standard channel with another channel of the plurality of channels having an above-standard quality; and (f) computing second LAT values based on the replacement cardiac channel.