Cardiac Electrogram Artifact Detection via Beat Periodicity Analysis

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Solution Overview

Problem

Implantable medical devices often misinterpret artifacts in cardiac signals as tachyarrhythmias due to motion artifacts and other noise, leading to incorrect treatment decisions.

Innovation Solution

A system comprising a medical device with multiple electrodes and a processor that determines the derivative of a cardiac electrogram, detects periodic beats, and classifies cardiac rhythms to differentiate between treatable and nontreatable conditions based on beat periodicity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If implantable medical devices monitor cardiac signals using traditional methods, then they can detect cardiac arrhythmias, but they may misinterpret artifacts as tachyarrhythmias leading to false positives

Engineering Contradiction:
Improveaccuracy of tachyarrhythmia detectionVSAvoidfalse positive detection due to artifacts
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The detection process is segmented into multiple independent analysis stages: (1) derivative calculation of the electrogram signal, (2) beat detection within the derivative signal, (3) periodicity analysis of detected beats, and (4) artifact classification based on periodicity. This segmentation allows each stage to focus on specific characteristics, improving overall detection accuracy while reducing false positives from artifacts.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Instead of directly analyzing the electrogram signal for tachyarrhythmias, the invention inverts the approach by first calculating the derivative of the signal, then detecting beats in the derivative, and using the periodicity of these beats to identify artifacts. This inverted methodology transforms the detection problem from direct pattern recognition to indirect characterization through derivative analysis.

Inventive Principle:
Principle #13The other way round (Inversion)

2Measurement precision

If the device uses additional signal processing steps to differentiate artifacts from real arrhythmias, then detection accuracy improves, but device complexity increases

Engineering Contradiction:
Improveprecision of cardiac rhythm classificationVSAvoidcomplexity of signal processing algorithm
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The invention replaces complex mechanical or hardware-based filtering systems with a computational approach using derivative calculation and periodicity analysis. Instead of using multiple physical filters or complex analog circuits to differentiate artifacts, the system uses mathematical operations (derivative computation) followed by simple periodicity detection algorithms, achieving high precision with relatively simple device implementation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentEP2346399B1Periodic beat detection to detect artifacts in a cardiac electrogram
Publication Date: 2012.09.05 MEDTRONIC INC
  • EP2346399B1 patent drawingFigure 1
  • EP2346399B1 patent drawingFigure 2
  • EP2346399B1 patent drawingFigure 3

AI summary

Techniques for determining whether artifacts are present in a cardiac electrogram are described. According to one example, a medical device senses a cardiac electrogram via electrodes. The medical device determines a derivative, e.g., a second order derivative, the electrogram. The medical device detects beats within the derivative, e.g., by comparing a rectified version of the derivative to one or more thresholds determined based on a maximum of the rectified derivative. The medical device determines whether the beats are periodic, and determines whether artifacts are present in the cardiac electrogram based on the determination of whether the beats are periodic. The medical device may further determine whether tachyarrhythmia is present and/or whether the cardiac rhythm of the patient is treatable based on the determination of whether the beats are periodic. For example, the medical device may determine that an electrogram is not treatable when the beats are periodic.