Cardiac Image Synchronization via Non-Linear Time Warping

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Solution Overview

Problem

Existing cardiac imaging methods fail to accurately synchronize image sequences acquired at different heart rates, leading to time-distorted representations of heart behavior during medical procedures.

Innovation Solution

The method employs non-linear time warping to synchronize image sequences based on the non-linear dependence of cardiac cycle phases on heartbeat rates, using a piecewise linear function to adjust presentation times and ensure accurate alignment along the cardiac cycle.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If linear synchronization methods are used to align image sequences acquired at different heart rates, then the synchronization process is simple and fast, but time distortions occur in the representation of heart behavior

Engineering Contradiction:
Improvesynchronization process simplicityVSAvoidtime alignment accuracy
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent transforms the synchronization approach by changing from linear time scaling to non-linear time warping. The system divides the cardiac cycle into multiple phases (e.g., isovolumetric contraction, ejection, isovolumetric relaxation, filling) and applies different time scaling factors to each phase based on the relationship between heart rate and phase duration. This allows accurate representation of heart behavior at different rates while maintaining computational feasibility.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent segments the cardiac cycle into distinct physiological phases, each with its own time-duration characteristics. By identifying key events (e.g., valve openings/closings, peak contraction) and dividing the cycle accordingly, the system can apply phase-specific time warping functions. This segmentation enables precise control over time alignment in each phase while preserving the overall cardiac cycle structure.

Inventive Principle:
Principle #1Segmentation

2Manufacturing precision

If non-linear time warping is applied to accurately synchronize cardiac phases, then time alignment accuracy improves, but computational complexity increases

Engineering Contradiction:
Improvetime alignment accuracyVSAvoidsynchronization algorithm complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent pre-computes time warping functions based on established physiological relationships between heart rate and cardiac phase durations. These functions are derived offline and stored for rapid application during synchronization. By performing the complex non-linear transformation calculations in advance, the system reduces real-time computational burden while maintaining high accuracy during actual image sequence synchronization.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent implements a dynamic synchronization approach where time scaling factors are adjusted based on the instantaneous heart rate and the specific cardiac phase being synchronized. Rather than applying a fixed global scaling factor, the system dynamically modifies time parameters for each phase according to the measured heart rate, allowing accurate adaptation to varying cardiac conditions while using computationally efficient lookup tables and interpolation methods.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentEP2905951B1Synchronizing between image sequences of the heart acquired at different heartbeat rates
Publication Date: 2020.05.27 BIOSENSE WEBSTER (ISRAEL) LTD
  • EP2905951B1 patent drawingFigure 1
  • EP2905951B1 patent drawingFigure 2
  • EP2905951B1 patent drawingFigure 3

AI summary

A method for performing a medical procedure includes holding a non-linear dependence between the duration of a given phase within a cardiac cycle and a respective heartbeat rate. First and second image sequences of the dynamic activity of the heart of a patient, acquired at respective different first and second heartbeat rates of the heart, are received. Synchronization between the first and second image sequences is performed based on the non-linear dependence, on the first and second heartbeat rates, and on a given common heartbeat rate. The first and second image sequences are played in synchronization with the common heartbeat rate.