Multi-site Cardiac Stimulation Vector Optimization
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Solution Overview
Problem
Current multi-site cardiac stimulation methods for treating congestive heart failure are complex and inefficient, requiring more energy and posing challenges in identifying suitable patients and determining optimal stimulation vectors, timing, and intensity parameters.
Innovation Solution
A system that uses physiological signals to determine stimulation vectors and therapy modes for multi-site cardiac stimulation, including chronological order and timing offsets, to deliver effective electrostimulation to multiple sites within the heart, improving cardiac performance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multi-site stimulation is applied to treat congestive heart failure, then cardiac performance is improved, but energy consumption increases
Solution Approach 1:
The system dynamically adjusts stimulation parameters including timing offsets between sites, stimulation intensity, and chronological ordering of multi-site deliveries based on sensed physiological signals to optimize cardiac performance while minimizing energy consumption
Solution Approach 2:
The system senses physiological signals from the heart and uses this feedback to determine optimal stimulation vectors and therapy modes, creating a closed-loop control system that adapts stimulation parameters to actual cardiac response
2Reliability
If multi-site stimulation is used to stimulate multiple cardiac sites, then therapeutic effectiveness is improved, but system complexity increases
Solution Approach 1:
The system divides the cardiac chamber into multiple discrete stimulation sites with separate electrodes, allowing independent control of each site while maintaining overall system manageability through modular electrode design
Solution Approach 2:
The system dynamically selects and switches between different stimulation vectors and therapy modes based on real-time physiological sensing, allowing the complexity to be managed through adaptive algorithms rather than fixed complex wiring
3Reliability
If multiple stimulation vectors are employed for multi-site stimulation, then cardiac performance improvement is enhanced, but difficulty in determining optimal parameters increases
Solution Approach 1:
The system uses physiological signal feedback to automatically determine optimal stimulation vectors and timing parameters, replacing manual trial-and-error optimization with automated sensing and decision algorithms
Solution Approach 2:
The system performs self-optimization by sensing its own stimulation effects and automatically adjusting parameters to achieve optimal cardiac performance without requiring extensive external programming or adjustment
4Reliability
If timing offsets and chronological order are controlled for multi-site stimulation, then therapeutic efficacy is improved, but operational complexity increases
Solution Approach 1:
The system automatically determines and adjusts timing offsets and chronological order of stimulations based on sensed physiological signals, eliminating the need for manual programming of complex timing parameters while maintaining therapeutic efficacy
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system enhances the efficiency and effectiveness of multi-site cardiac stimulation, improving patient outcomes by optimizing stimulation parameters and reducing energy consumption, while simplifying system design and operation.
Implementation Method 1
The electrodes may be electrically coupled to an electronics unit such as a pulse generator, such as via a lead, and may be used to deliver one or more electro stimulations to the heart
Implementation Method 2
The system may sense a physiological signal including during electrostimulation of the heart, use the physiological signal to determine at least a first stimulation vector
Data Source
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AI summary
Systems and methods for multi-site cardiac stimulation are disclosed. The system includes an electrostimulation circuit to deliver electrostimulation to one or more candidate sites of at least one heart chamber. The system may sense a physiological signal including during electrostimulation of the heart, use the physiological signal to determine a first stimulation vector for electrostimulation at a first left ventricular (LV) site and a second stimulation vector for electrostimulation at a different second LV site, and determine a therapy mode including a first chronological order and a first timing offset between stimulations delivered according to the first and second stimulation vectors. The electrostimulation circuit may deliver electrostimulation to the heart in accordance with the first and second stimulation vectors and the therapy mode.