Cardiovascular Compression Device Synchronization
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Solution Overview
Problem
Current methods for treating cardiovascular diseases and vascular pathologies of the limbs, such as obliterating atherosclerosis and diabetic angiopathy, are limited by the inability to create an effective antegrade blood pressure wave due to lack of selectivity and synchronization with cardiac activity, leading to reduced efficacy in blood flow enhancement.
Innovation Solution
The method involves periodical compression of limbs with pressure impulses synchronized with the QRS-complex of ECG, with delayed impulses in proximal and distal areas to align with blood flow pulse waves, using compression cuffs connected to a gas-distribution unit and a control unit that adjusts impulse parameters based on real-time blood flow measurements.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If independently managed compressive cuffs are used to create an antegrade wave of blood pressure, then blood flow enhancement is achieved, but synchronization with QRS-complexes is lost which reduces efficacy
Solution Approach 1:
The system uses ECG monitoring to detect QRS-complexes and provides real-time feedback to the control unit, which adjusts the compression timing accordingly. This closed-loop feedback mechanism ensures that compression impulses are synchronized with cardiac activity while maintaining blood flow enhancement effects.
Solution Approach 2:
The compression parameters (timing, duration, pressure) are dynamically adjusted based on the detected cardiac cycle phase. The system transitions from static, fixed-timing compression to dynamic, adaptive compression that responds to real-time physiological signals, resolving the contradiction between maintaining blood flow enhancement and achieving cardiac synchronization.
2Productivity
If compression impulses are generated with delay in relation to QRS-complex, then antegrade wave creation is improved, but the descending part must finish prior to systole initiation which limits functional capacity
Solution Approach 1:
The compression system is divided into multiple independently controlled compression elements (cuffs) that can be activated at different timing phases. This segmentation allows one cuff to provide the delayed compression for antegrade wave creation while another cuff can provide earlier compression for broader functional effects, resolving the contradiction between specialized antegrade wave creation and overall functional versatility.
3Stress or pressure
If high-pressure compressor is used to provide compressed air to compression cuffs, then compression efficacy is improved, but power consumption and mass-dimensional characteristics increase considerably
Solution Approach 1:
Instead of maintaining continuous high pressure, the system uses periodic compression impulses synchronized with the cardiac cycle. The compressor operates intermittently to deliver brief high-pressure bursts only when needed for compression, rather than maintaining constant high pressure. This periodic action maintains compression efficacy while dramatically reducing overall power consumption and system size.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach generates an effective antegrade pressure wave synchronized with the cardiac cycle, enhancing blood flow in distal regions and improving vascular health by increasing blood flow velocity and shearing stress, leading to vessel opening and angiogenesis.
Implementation Method 1
generates an effective antegrade pressure wave synchronized with the cardiac cycle, enhancing blood flow in distal regions
Implementation Method 2
pressure impulses synchronized with QRS-complex parameters of the ECG
Data Source
AI summary
The proposed method and devices provide for an effective improvement of the blood flow in the vessels of a human's extremities due to generation of an ante-grade pressure wave of blood synchronized with phases of the cardiac cycle with the help of compression impulses. The devices provide an improved accuracy of the time and amplitude characteristics of the compression impulses and functioning in modes of generation both the ante-grade wave and external counter-pulsation.


