Cassette Pressing Mechanism with Real-Time Force Detection

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Solution Overview

Problem

During the embedding process of tissue samples in paraffin blocks, the cassette containing the tissue sample is often manually held, leading to potential damage and poor quality of the resulting block due to improper pressing into the mold.

Innovation Solution

A device with a pressing member, abutment member, and sensor system that measures pressing force in real time, ensuring stable and controlled embedding by detachably mounting to a guide member and using elastic members to adjust force on the cassette frames.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual holding of cassette is used during embedding process, then ease of operation is improved, but reliability of tissue sample integrity deteriorates

Engineering Contradiction:
Improveease of operationVSAvoidreliability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent replaces manual mechanical holding with an automated pressing device that uses a sensor (force sensor/pressure sensor) to detect and control pressing force. The sensor system substitutes human tactile control with precise mechanical sensing, eliminating manual operation risks while maintaining reliability through controlled force application.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The pressing device incorporates a force sensor or pressure sensor that provides real-time feedback on the pressing force applied to the cassette. This feedback mechanism allows the system to monitor and adjust the pressing force automatically, ensuring tissue sample integrity while maintaining ease of operation through automated control.

Inventive Principle:
Principle #23Feedback

2Manufacturing precision

If pressing force is increased to improve embedding quality, then manufacturing precision is improved, but object-affected harmful factors increase

Engineering Contradiction:
Improvemanufacturing precisionVSAvoidobject-affected harmful factors
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent uses a sensor to detect and measure pressing force parameters in real-time, allowing precise control of the pressing force applied to the cassette. By monitoring and adjusting the force parameter, the system achieves high embedding quality while preventing excessive force that could damage the tissue sample, thus resolving the contradiction between manufacturing precision and harmful factors.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If sensor is added to measure pressing force, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvemeasurement precisionVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent introduces a sensor as an intermediary component between the pressing mechanism and the control system. This sensor acts as a mediator that provides precise force measurement without requiring complex direct measurement systems, simplifying the overall device architecture while achieving high measurement precision for pressing force control.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device enhances the stability and quality of paraffin blocks by precisely measuring and adjusting the pressing force on both outer and inner frames of the cassette, reducing the risk of tissue sample damage.

Implementation Method 1

a sensor coupled between the pressing member and the abutment member and configured to measure a pressing force on the cassette

Methodology Applied
Scientific EffectForce detection: Force

Implementation Method 2

an elastic member coupled between the pressing member and the mold and configured to force the pressing member towards the outer frame of the cassette

Methodology Applied
Scientific EffectElasticity: Elasticity

Data Source

PatentUS20250216302A1Device for pressing cassette and embedder having same
Publication Date: 2025.07.03 LEICA BIOSYSTEMS NUSSLOCH GMBH
  • US20250216302A1 patent drawing
  • US20250216302A1 patent drawing

AI summary

A device for pressing a cassette is provided. The cassette includes an outer frame and an inner frame mounted in the outer frame, and the cassette is configured to be held in a groove of a mold. The device includes a pressing member; an abutment member configured to abut against the cassette; a sensor coupled between the pressing member and the abutment member and configured to measure a pressing force on the cassette, and a guide member configured to be mounted on the mold. The pressing member is detachably mounted to the guide member and slidable on the guide member in a vertical direction. The pressing force on the cassette can be detected in real time by the device according to the present disclosure.