Hydrophilic Urinary Catheter Coating With Triggered Antimicrobial Release

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Solution Overview

Problem

Existing urinary catheters are prone to contamination, leading to urinary tract infections due to bacterial introduction during use, despite being prepared in sterile environments and following safe handling instructions.

Innovation Solution

A urinary catheter product with a hydrophilic polymer coating and embedded microcapsules containing an anti-microbial agent, which releases upon exposure to irradiation or pH change, providing antimicrobial protection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If catheters are prepared in sterile environments with safe handling instructions, then initial sterility is maintained, but contamination risk increases during use due to bacterial introduction and carry-along

Engineering Contradiction:
Improvesterility maintenanceVSAvoidbacterial contamination
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent incorporates anti-microbial agents into the catheter structure in advance (in the lumen, on the outer surface, or both), so that the protective action is already in place before use. This preliminary incorporation ensures that when bacteria are introduced during catheterization, the anti-microbial agents are immediately available to neutralize them, rather than relying solely on pre-packaging sterility which cannot protect against contaminants introduced during the procedure itself

Inventive Principle:
Principle #10Preliminary action

2Reliability

If anti-microbial agents are incorporated into the catheter, then protection against urinary tract infections is improved, but device complexity increases due to multiple incorporation methods

Engineering Contradiction:
Improveinfection protectionVSAvoidincorporation structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent divides the anti-microbial protection into separate functional segments: agents incorporated into the lumen for internal protection against bacteria introduced during catheterization, and agents incorporated into the outer surface for protection against environmental contaminants. This segmentation allows each region to address specific contamination risks independently, providing comprehensive protection while maintaining clear functional differentiation that simplifies the overall design logic

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The catheter is designed to perform multiple protective functions simultaneously through a single integrated structure. The same catheter body incorporates anti-microbial agents in both the lumen and outer surface, enabling it to protect against both internal contamination (from the catheterization procedure) and external contamination (from the environment), thereby providing universal protection against multiple contamination pathways

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively reduces the risk of urinary tract infections by releasing anti-microbial agents at the right moment, enhancing catheter hygiene and user safety.

Implementation Method 1

The microcapsules are configured to release the anti-microbial agent upon irradiation

Methodology Applied
Scientific EffectIrradiation: Radiation

Implementation Method 2

The microcapsules are configured to release the anti-microbial agent upon exposure to a pH range

Methodology Applied
Scientific EffectpH exposure:

Implementation Method 3

a hydrophilic polymer coating on an outer surface of the catheter tube

Methodology Applied
Scientific EffectHydrophilic absorption: Absorption (physical)

Data Source

PatentEP4518922B1Hydrophilic urinary catheter products with microcapsules of Anti-bacterial agents
Publication Date: 2025.12.03 HOLLISTER INCORPORAED
  • EP4518922B1 patent drawingFigure 1~2
  • EP4518922B1 patent drawingFigure 3
  • EP4518922B1 patent drawingFigure 4~5

AI summary

A catheter product including a urinary catheter with anti-microbial microcapsules. More particularly a urinary catheter with anti-microbial microcapsules that release the anti-microbial agent upon exposure to irradiation.