Hydrophilic Urinary Catheter Coating to Inhibit Bacterial Swarming

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Solution Overview

Problem

Urinary catheters often introduce bacteria into the urethra due to contamination during use, leading to urinary tract infections, especially in non-voiding patients, as urine flow is disrupted and urethral mucus viscosity is diluted by hydrophilic coatings or lubricants, activating bacterial motility.

Innovation Solution

A urinary catheter with a hydrophilic coating and hydration medium containing a compound to retain or increase urethral mucus viscosity, using desiccants or thickening agents to maintain or enhance the urethral environment's viscosity, preventing bacterial swarming.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a hydrophilic coating is applied to the catheter shaft to improve lubricity and reduce tissue damage, then patient comfort is improved, but the coating dilutes urethral mucus viscosity which activates bacterial motility and increases infection risk

Engineering Contradiction:
Improvecatheter insertion comfortVSAvoidbacterial motility activation
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent modifies the chemical composition parameters of the lubricating coating by incorporating viscousifying agents (polymers, glycerin, propylene glycol) into the hydrophilic coating formulation. This changes the rheological properties of the coating to maintain higher viscosity in the urethral environment, thereby reducing bacterial motility activation while preserving lubricity benefits

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite lubricating coating material that combines hydrophilic polymers with viscousifying agents. This composite material provides both the lubrication properties needed for comfortable insertion and the viscosity-maintaining properties needed to inhibit bacterial motility, resolving the contradiction between comfort and infection risk

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If lubricants are applied to the catheter surface to reduce soft tissue damage, then tissue trauma is reduced, but urethral mucus viscosity is diluted which promotes bacterial swarming toward the bladder

Engineering Contradiction:
Improvesoft tissue damageVSAvoidbacterial introduction
Core Design Contradiction:
Object-affected harmful factorsVSObject-generated harmful factors

Solution Approach 1:

The patent changes the physical-chemical parameters of the lubricant by formulating it with high-viscosity components and viscousifying agents. This modification allows the lubricant to provide tissue protection while maintaining sufficient viscosity to prevent bacterial swarming, thus resolving the contradiction between reducing tissue damage and preventing bacterial introduction

Inventive Principle:
Principle #35Parameter changes

3Productivity

If urine flow is disrupted by catheter insertion, then continuous bladder drainage is achieved, but urethral flushing function is lost allowing bacteria to accumulate and increase infection risk

Engineering Contradiction:
Improvebladder drainage efficiencyVSAvoidbacterial accumulation
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent introduces viscousifying agents as intermediary substances in the lubricating coating that serve dual functions: they maintain coating lubricity for comfortable insertion and create a viscosity barrier that inhibits bacterial motility. This intermediary substance compensates for the loss of natural urethral flushing function while maintaining drainage efficiency

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The catheter design inhibits bacterial motility and reduces the risk of urinary tract infections by keeping bacteria static in the urethra, preventing them from traveling to the bladder.

Implementation Method 1

a hydrophilic coating on the catheter shaft (16); a hydration medium (18) for hydrating the hydrophilic coating

Methodology Applied
Scientific EffectHydrophilic absorption: Absorption (physical)

Implementation Method 2

the compound comprises a desiccant that removes moisture from the urethral mucus

Methodology Applied
Scientific EffectDesiccation: Desiccation

Data Source

PatentEP4051328B1Urinary catheters and methods for preventing bacterial infections
Publication Date: 2026.03.11 HOLLISTER INCORPORAED
  • EP4051328B1 patent drawingFigure 1~2

AI summary

Urinary catheters and methods for preventing bacterial infections.