Catheter Electrode Spatial Arrangement for Orientation-Independent Mapping

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Solution Overview

Problem

Conventional catheter systems face challenges in accurately characterizing cardiac conduction conditions due to limitations in electrode spacing and orientation, which affect the reliability of signal discrimination and localization of defects, especially in small regions, leading to incomplete or ineffective ablation treatments for arrhythmias.

Innovation Solution

A system and method utilizing closely spaced electrodes with an electronic control unit to determine catheter orientation-independent electrophysiological data, compensating for artifacts and resolving local electric fields into components aligned with anatomy, enabling more precise characterization of cardiac conduction and ablation effectiveness.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If electrode pairs are spaced greater than 4 mm apart, then the catheter structure is simpler and easier to manufacture, but the ability to discriminate or localize defects is reduced

Engineering Contradiction:
Improvecatheter structure simplicityVSAvoiddefect localization accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The catheter electrode array is segmented into multiple closely spaced electrode pairs (approximately 1-2 mm apart) along the catheter shaft, allowing fine-grained spatial sampling of electrical signals to accurately localize small conduction defects while maintaining manageable manufacturing through modular electrode assembly

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If electrodes are spaced closer together (1-2 mm), then defect localization improves, but the orientation of the electrode pair becomes a prominent factor in signal amplitude and morphology

Engineering Contradiction:
Improvedefect localization accuracyVSAvoidcatheter orientation independence
Core Design Contradiction:
Measurement precisionVSAdaptability or versatility

Solution Approach 1:

Multiple closely spaced electrode pairs are combined into a comprehensive mapping system that records signals from all electrode pairs and uses computational algorithms to integrate the data, producing orientation-independent activation maps that compensate for the directional sensitivity of individual electrode pairs

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The mechanical/orientational dependency of individual electrode signals is replaced through computational processing that transforms the data into a coordinate system independent of catheter orientation, using algorithms that calculate activation times and vectors based on the spatial arrangement of multiple electrodes rather than relying on single-pair orientation

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Ease of manufacture

If conventional electrode spacing is used, then the catheter is easier to manufacture, but conduction disorders in small regions (1-4 mm) cannot be reliably detected

Engineering Contradiction:
Improvecatheter manufacturing simplicityVSAvoidconduction disorder detection accuracy
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

The catheter is segmented into multiple closely spaced electrode pairs (1-2 mm apart) that create a high-density sampling array, enabling reliable detection of conduction disorders in small regions (1-4 mm) through fine-grained spatial resolution while maintaining manufacturing feasibility through standardized electrode fabrication processes

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system transitions from conventional single-pair or widely spaced electrode measurements to a multi-dimensional array of closely spaced electrodes, creating a three-dimensional mapping capability that provides both spatial resolution for small regions and redundant measurements for reliable detection

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for more reliable and accurate substrate amplitude mapping, scar border delineation, and conduction velocity assessment, facilitating faster and more successful therapeutic procedures by providing catheter orientation-independent electrophysiologic information.

Implementation Method 1

Such navigating systems may include, for example, electric and/or magnetic field based positioning and navigating systems that are able to determine the position and orientation of the catheter (and similar devices) within the body

Methodology Applied
Scientific EffectElectromagnetic field positioning: Electric Field

Implementation Method 2

The catheter carries one or more electrodes that can be used for cardiac mapping or diagnosis, ablation and/or other therapy delivery modes

Methodology Applied
Scientific EffectElectrical signal detection: Electric Field

Data Source

PatentEP3733060B1Utilization of electrode spatial arrangements for characterizing cardiac conduction conditions
Publication Date: 2021.06.16 ST JUDE MEDICAL ATRIAL FIBRILLATION DIVISION INC
  • EP3733060B1 patent drawingFigure 1
  • EP3733060B1 patent drawingFigure 2
  • EP3733060B1 patent drawingFigure 3A~3C

AI summary

A system for determining electrophysiological data, comprising an electronic control unit configured to receive electrogram data for a set of electrodes, wherein the electrogram data comprises a plurality of unipole signals and a plurality of bipole signals; receive position and orientation information for the set of electrodes from a mapping system; compose a clique comprising a subset of neighboring electrodes in the set of electrodes, wherein each clique comprises at least three electrodes from the set of electrodes; derive a local E-field from one of the plurality of bipole signals and the plurality of unipole signals of the clique; determine catheter orientation independent information of a tissue based on the local E-field; and output the orientation independent information to a user or process.