Catheter Localization in HDR Brachytherapy

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Solution Overview

Problem

Current high dose rate (HDR) brachytherapy methods for prostate cancer face challenges in accurately localizing catheters due to cumbersome catheter segmentation in ultrasound images and errors caused by electromagnetic tracker calibration and magnetic field variations, leading to potential under- or over-dosage of tissue.

Innovation Solution

An image-based registration method that directly registers electromagnetic-tracked catheters to the ultrasound coordinate system using ultrasound image content, eliminating the need for EM-grid registration and allowing for optically tracked or non-tracked ultrasound probes, thereby correcting positioning errors and simplifying the procedure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Difficulty of detecting and measuring

If electromagnetic tracking is used to localize catheters, then catheter position detection is enabled, but positioning accuracy deteriorates due to calibration errors and magnetic field variations

Engineering Contradiction:
Improvecatheter position detectionVSAvoidcatheter localization accuracy
Core Design Contradiction:
Difficulty of detecting and measuringVSMeasurement precision

Solution Approach 1:

The patent introduces an intermediary registration process that maps EM tracker coordinates to ultrasound image coordinates through identified features (calcifications, catheter segments). This intermediary transformation layer corrects systematic errors between the EM tracking system and the actual catheter positions by using visible anatomical landmarks as reference points, thereby improving localization accuracy without eliminating EM tracking.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system implements feedback by detecting the position of identifiable features (calcifications, catheter segments) in ultrasound images and using this information to correct the EM tracker positioning. The registered feature positions provide feedback that compensates for calibration errors and magnetic field variations, continuously improving measurement precision throughout the procedure.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If manual segmentation of catheters in ultrasound images is performed to correct positioning errors, then localization accuracy is improved, but time consumption and operational complexity increase

Engineering Contradiction:
Improvecatheter localization accuracyVSAvoidtime for manual segmentation
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system enables self-service by automatically detecting and segmenting catheters and identifiable features directly from ultrasound images without requiring manual intervention. The automated image processing algorithms identify catheter positions, calcifications, and other anatomical landmarks, performing the segmentation task that would otherwise require time-consuming manual work, thus reducing both time loss and operational complexity while maintaining high localization accuracy.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If EM-grid registration is used to correct positioning errors, then catheter localization accuracy is improved, but device complexity and procedural steps increase

Engineering Contradiction:
Improvecatheter localization accuracyVSAvoidregistration system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and eliminates the separate EM-grid registration step from the procedural workflow. Instead of requiring a distinct grid-based calibration phase, the system directly registers EM tracker positions to ultrasound images by identifying features within the image data itself. This extraction of the grid registration step simplifies the overall device complexity and reduces procedural steps while maintaining the ability to correct positioning errors through direct image-based feature matching.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentEP2996587B1Instrument localization in guided high dose rate brachytherapy
Publication Date: 2022.08.24 KONINKLIJKE PHILIPS NV
  • EP2996587B1 patent drawingFigure 1
  • EP2996587B1 patent drawingFigure 2
  • EP2996587B1 patent drawingFigure 3

AI summary

A system for localizing one or more medical instruments includes a guidance grid (162) disposed in an operative relationship with a subject for receiving the one or more medical instruments (102) when deployed. An ultrasound imaging system (110) is configured to image a volume where the one or more medical instruments are deployed. A program module (136) is configured to register positions of the one or more medical instruments, using tracked position information and grid information, to the volume such that the positions of the one or more medical instruments can be visually monitored during a procedure.