Catheter Pressure Sensor Integration for Safe Reperfusion
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Solution Overview
Problem
Current medical devices and perfusion systems face challenges in effectively detecting fluid pressure and transferring fluids past obstructions in blood vessels, such as arterial occlusions, which can lead to inadequate reperfusion and tissue damage during procedures like stroke treatment.
Innovation Solution
The development of medical devices with integrated pressure sensors and perfusion systems that include elongated bodies with separate lumens for sensors, stiffeners, and thermoregulation, allowing for controlled fluid infusion and pressure monitoring to ensure safe and effective reperfusion beyond obstruction sites.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If pressure sensors are integrated into the catheter wall, then real-time pressure monitoring is achieved, but the device complexity increases
Solution Approach 1:
The patent integrates the pressure sensor directly into the catheter wall structure, merging the sensing function with the structural component. This allows real-time pressure monitoring within the fluid-filled space while maintaining a unified device architecture rather than adding separate monitoring systems.
Solution Approach 2:
The catheter wall is designed to serve multiple functions: providing structural support, containing the fluid-filled space, and housing the pressure sensor for monitoring. This multi-functionality reduces the need for separate components and minimizes overall device complexity while achieving accurate pressure measurement.
2Ease of manufacture
If separate sensor lumens are created in the catheter wall, then sensor integration is improved, but manufacturing complexity increases
Solution Approach 1:
The sensor lumen is pre-formed within the catheter wall structure during manufacturing, allowing the pressure sensor to be subsequently integrated into a ready-made channel. This preliminary preparation simplifies the overall integration process and reduces assembly complexity despite adding a manufacturing step.
Solution Approach 2:
The catheter wall is segmented to include a dedicated sensor lumen that is spatially separated from the main fluid pathway. This segmentation allows independent access and integration of the pressure sensor without interfering with the primary fluid flow functions, simplifying both manufacturing and maintenance.
3Adaptability or versatility
If multiple lumens are positioned in the catheter wall, then functional separation is achieved, but device complexity increases
Solution Approach 1:
The patent positions multiple lumens in different spatial dimensions within the catheter wall, including radial and axial arrangements. This dimensional organization allows multiple functions (fluid flow, pressure sensing, thermoregulation) to be accommodated without excessive structural complexity by efficiently utilizing available space in three-dimensional configuration.
Solution Approach 2:
The sensor lumen is nested within the catheter wall structure, with the pressure sensor positioned inside the pre-formed lumen channel. This nesting approach allows compact integration of multiple functions within the catheter wall thickness, maximizing functional versatility while minimizing overall device diameter and structural complexity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables controlled and safe reperfusion downstream of obstructions, reducing the risk of vascular compromise and tissue damage by monitoring and managing fluid pressure, thereby facilitating restoration of blood flow and metabolic protection in obstructed vessels.
Implementation Method 1
The heating may be accomplished through an infrared heater
Data Source
AI summary
Medical devices, perfusion systems, and methods for detecting a pressure within a space in a subject and for perfusion of fluid into a space in a subject. The space may be a fluid-filled space, or a space that is depleted of fluid due to an obstruction to fluid flow into the space. Methods for forming the medical devices.


