Cavitation Cleaning Nozzle for Pharmaceutical Residue Removal
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Solution Overview
Problem
Current cleaning devices lack sufficient capability to remove residues from pharmaceutical manufacturing machine components and medical instruments, particularly those stuck due to pharmaceutical residues or body fluids, leading to uneven cleaning and compliance issues with Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) standards.
Innovation Solution
A cleaning device with a venturi tube structure and a gas-liquid mixture nozzle that uses a pressured cleaning fluid and carbon dioxide to create a high-flow, cavitation-inducing jet for efficient removal of residues from complex-shaped objects, ensuring thorough cleaning without chemical contamination.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If high-pressure water is used for cleaning, then cleaning speed is improved, but cleaning capability for stuck residues is insufficient
Solution Approach 1:
The patent changes the parameters of the cleaning fluid by mixing gas (carbon dioxide) with liquid (water) to create a gas-liquid mixture. This mixture is then pressurized to high pressure and ejected through a nozzle with a specific flow passage cross-sectional area ratio to generate cavitation. The parameter change from simple high-pressure water to cavitation-inducing gas-liquid mixture resolves the contradiction by providing both high cleaning speed and enhanced cleaning capability for stuck residues.
Solution Approach 2:
The patent utilizes phase transitions of the cleaning fluid by creating a gas-liquid mixture that undergoes cavitation (liquid-to-gas phase transition) when ejected at high pressure. The cavitation bubbles collapse and generate intense local cleaning action that effectively removes stuck residues. This phase transition mechanism enables the cleaning device to achieve both high cleaning speed and superior cleaning capability simultaneously.
2Reliability
If chemical cleaning agents are used, then cleaning capability is improved, but chemical contamination and validation issues occur
Solution Approach 1:
The patent replaces chemical cleaning mechanisms with a physical cleaning mechanism based on high-pressure gas-liquid mixture ejection and cavitation. Instead of using chemical agents to dissolve and remove residues, the system uses mechanically generated cavitation bubbles that collapse to create intense localized cleaning force. This substitution eliminates chemical contamination while maintaining or enhancing cleaning capability for stuck residues.
Solution Approach 2:
The patent employs pneumatic and hydraulic principles by using pressurized gas (carbon dioxide) mixed with liquid (water) to create a high-velocity jet. The pneumatic pressure drives the hydraulic fluid through a specially designed nozzle that generates cavitation. This gas-liquid dynamics approach provides powerful mechanical cleaning action without requiring chemical agents, thus avoiding chemical contamination and validation issues.
3Reliability
If manual cleaning with brush is used, then cleaning capability is improved, but operation complexity increases
Solution Approach 1:
The patent implements self-service cleaning by using the cleaning fluid itself to generate the cleaning action through cavitation. The high-pressure gas-liquid mixture automatically generates cavitation bubbles that collapse on contact with residues, providing self-enhancing cleaning capability without requiring manual brush intervention. This automation maintains superior cleaning capability while dramatically simplifying operation.
Solution Approach 2:
The patent replaces the manual mechanical brushing action with an automated high-pressure gas-liquid jet system that generates cavitation. Instead of requiring operators to manually scrub surfaces with brushes, the system uses pressurized fluid dynamics and cavitation to automatically remove residues. This substitution maintains effective cleaning capability while eliminating the operational complexity and labor intensity of manual brushing.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device effectively removes residues from both pharmaceutical manufacturing machine components and medical instruments with high cleaning capability, ensuring compliance with quality and safety standards by using a high-flow gas-liquid mixture to physically dislodge and chemically assist in the removal of stuck materials.
Implementation Method 1
a cleaning fluid discharge portion which is connected to the cleaning fluid retention portion, and discharges the cleaning fluid retained in the cleaning fluid retention portion to the cleaning portion in a pressured state
Implementation Method 2
a cleaning portion which ejects the cleaning fluid, in the cleaning tank... a first flow passage which is connected to the cleaning fluid discharge portion, and to which the cleaning fluid which is pressure-fed by the cleaning fluid discharge portion is supplied; a second flow passage which is continued to a downstream end of the first flow passage, and of which a flow passage cross-sectional area is smaller than that of the first flow passage; a third flow passage which is continued to a downstream end of the second flow passage, and of which the flow passage cross-sectional area becomes gradually larger as being separated from the second flow passage
Implementation Method 3
A cleaning device with a venturi tube structure and a gas-liquid mixture nozzle that uses a pressured cleaning fluid and carbon dioxide to create a high-flow, cavitation-inducing jet
Data Source
AI summary
A cleaning device (100) according to the present invention is constituted by including in a cleaning nozzle member (21) provided inside a cleaning tank (2): a large pipe diameter part (211) that supplies a cleaning fluid (31) pressure-fed from a retention tank (3); a small pipe diameter part (212) that increases the speed of a flow rate for the cleaning fluid (31) flowing in the large pipe diameter part; a conical pipe diameter part (213) that generates a fluid that includes minute bubbles by cavitation; and a guide pipe diameter part (214) for accommodating an object (5) to be cleaned. The cleaning fluid (31) is ejected to the entirety of the object (5).


