CB121 Inbred Corn Line for Stable High-Yield Hybrid Breeding

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Solution Overview

Problem

There is a need for developing stable, high-yielding corn hybrids with superior parental lines that exhibit desirable traits for maximizing ear and kernel production, while also providing resistance to pests, diseases, and environmental stress, and enhancing nutritional quality.

Innovation Solution

The development of a novel inbred corn line, CB121, which can be used in breeding programs to introduce traits such as male sterility, herbicide resistance, insect resistance, disease resistance, and improved nutritional quality through methods like mutagenesis, TILLING screening, and genetic transformation, utilizing transgenes and regulatory elements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional breeding methods are used to develop corn hybrids, then genetic stability can be maintained, but yield potential and agronomic superiority are limited

Engineering Contradiction:
Improveyield potentialVSAvoidagronomic adaptability
Core Design Contradiction:
ProductivityVSAdaptability or versatility

Solution Approach 1:

The patent applies parameter changes by modifying genetic parameters through the introduction of transgenes (Bt gene for insect resistance, herbicide resistance genes) into the corn inbred line. This transforms the genetic composition to achieve superior agronomic traits including enhanced yield potential, disease resistance, and adaptability across different environmental conditions, while maintaining the foundational genetic stability of the inbred line CB121

Inventive Principle:
Principle #35Parameter changes

2Reliability

If transgenes are introduced to improve specific traits, then agronomic characteristics are enhanced, but genetic complexity increases

Engineering Contradiction:
Improvedisease resistanceVSAvoidgenetic complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies the taking out principle by isolating and introducing specific functional genes (Bt gene for insect resistance, herbicide resistance genes) into the corn genome. This extracts only the necessary genetic elements required for enhanced disease and insect resistance, rather than introducing complex genetic material, thereby improving reliability while minimizing increases in overall genetic complexity

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent applies local quality by introducing transgenes that confer specific localized functions (insect resistance in leaf tissue, herbicide resistance in meristematic tissue) without altering the overall genetic architecture of the inbred line. This allows targeted enhancement of specific agronomic traits while maintaining the genetic stability and uniformity of the foundational CB121 inbred line

Inventive Principle:
Principle #3Local quality

3Stability of the object's composition

If inbred lines are developed for hybrid production, then genetic uniformity is achieved, but hybrid development time and complexity increase

Engineering Contradiction:
Improvegenetic uniformityVSAvoidbreeding cycle time
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-developing the CB121 inbred line with desired agronomic traits through prior genetic modification and stabilization. This preliminary development of a genetically uniform and agronomically superior inbred line serves as a ready-to-use parental line for hybrid production, reducing the time and complexity required for subsequent hybrid development while maintaining genetic uniformity across generations

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12628763B2Inbred corn line CB121
Publication Date: 2026.05.19 KWS SAAT SE & CO KGAA

AI summary

Inbred corn line, designated CB121, is disclosed. The disclosure relates to the seeds of inbred corn line CB121, to the plants and plant parts of inbred corn line CB121 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred corn line CB121 with itself or another com line. The disclosure also relates to products produced from the seeds, plants, or parts thereof, of inbred corn line CB121 and/or of the hybrids produced using the inbred as a parent. The disclosure further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other corn lines derived from inbred corn line CB121.