CBD Body Cavity Gel for Mucoadhesive Pathogen Protection
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Solution Overview
Problem
There is a need for formulations, such as intra-nasal formulations, to prevent, reduce, and/or mitigate the risk of infection, allergies, or other symptoms triggered by airborne particles like dust, pollen, microorganisms, bacteria, fungi, and/or viruses, including COVID-19.
Innovation Solution
A composition comprising cannabidiol (CBD), glycols, non-ionic emulsifiers, NaCl, panthenol, hyaluronic acid/salt, phytic acid, and water, optionally with gelling agents and pH regulators, formulated as a gel with a neutral or slightly acidic pH, applied topically in body cavities to provide protection against pathogens and reduce infection risk.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional nasal formulations are used, then basic nasal delivery is achieved, but protection against pathogens and airborne particles is insufficient
Solution Approach 1:
The formulation combines multiple active ingredients (cannabinoids, menthol, eucalyptol, thymol, camphor) with specific excipients (glycols, emulsifiers, surfactants) to create a composite gel composition that provides both nasal delivery and enhanced pathogen protection through synergistic effects of the components
Solution Approach 2:
The gel formulation acts as an intermediary substance applied to the nasal mucosa that creates a protective barrier between the respiratory tract and airborne pathogens, using mucoadhesive properties to maintain prolonged contact and protection
2Duration of action of moving object
If gel formulations are used for nasal application, then prolonged contact time is achieved, but formulation complexity increases
Solution Approach 1:
The gel formulation serves multiple functions simultaneously: it provides mucoadhesion for prolonged contact, acts as a vehicle for delivering multiple active ingredients, creates a protective barrier against pathogens, and utilizes the emulsifying and surfactant properties of its components to maintain stability and efficacy
Solution Approach 2:
The formulation achieves prolonged contact time by adjusting the gel's rheological properties and mucoadhesive characteristics through careful selection of excipients like glycols and emulsifiers, while maintaining applicability by controlling viscosity and texture parameters
3Reliability
If multiple active ingredients are included for enhanced protection, then efficacy against multiple pathogens is improved, but manufacturing precision requirements increase
Solution Approach 1:
The formulation integrates multiple bioactive compounds (cannabinoids, terpenes, phenols) with specific functional excipients in defined concentration ranges, creating a composite composition where each component contributes to overall efficacy against different pathogen types while maintaining manufacturability through established pharmaceutical formulation practices
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition enhances tolerance to undesirable compounds, reduces infection risk, and mitigates symptoms by forming a protective barrier in body cavities, potentially increasing the dose required for triggering reactions and reducing contamination of infectious diseases.
Implementation Method 1
mucoadhesive delivery system
Implementation Method 2
hyaluronic acid/salt
Data Source
AI summary
The present invention relates to non-psychoactive cannabinoid-comprising compositions, said compositions comprising cannabidiol (CBD) formulated for application in a body cavity, such as a gel for intranasal application. Said composition comprises CBD; glycol(s); emulsifier(s), including non-ionic emulsifier(s); NaCl; panthenol; hyaluronic acid/salt; phytic acid and water, and optionally one or more of gelling agent, allantoin, and/or pH regulator. Such compositions can be used in the context of protection against pathogens and/or in reduction of ingress of infectious and/or irritating agents such as dust, pollen, microorganism(s), bacteria, fungi, and/or virus, such as COVID-19.