CBD Topical Composition Using Broccoli Seed Oil for Skin Penetration
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Solution Overview
Problem
Cannabidiol (CBD) exhibits low skin penetration due to its lipophilic nature, limiting its bioefficacy in topical applications, and existing formulations fail to optimize therapeutic penetration and absorption, with alternative methods like nano-particles not being suitable for cosmetic use.
Innovation Solution
A specific emulsion of CBD with botanicals, broccoli seed oil, Isoamyl Laurate, and cellulose increases CBD penetration in the skin, demonstrated by a formulation comprising CBD, broccoli seed oil, ethanol, aloe vera, and isoamyl laurate, enhancing penetration into the epidermis and dermis layers.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If CBD is extracted from plant material using conventional methods, then CBD can be obtained, but the extract contains harmful contaminants such as pesticides, heavy metals, and microbial impurities
Solution Approach 1:
The patent applies extraction by removing CBD from plant material using supercritical carbon dioxide, selectively extracting the desired compound while leaving contaminants behind in the plant residue. This separation process eliminates pesticides, heavy metals, and microbial impurities from the final CBD product.
Solution Approach 2:
The patent uses supercritical carbon dioxide as an inert extraction medium that does not introduce harmful contaminants. The CO2 system operates in a controlled inert environment that prevents introduction of pesticides, heavy metals, and microbial impurities, ensuring a clean extract.
2Productivity
If CBD is synthesized chemically, then CBD can be produced, but the synthesis process is complex and requires multiple steps with specialized equipment
Solution Approach 1:
The patent replaces complex chemical synthesis machinery and multi-step reaction equipment with a simpler supercritical fluid extraction system. The mechanical and chemical complexity of synthesis apparatus is substituted with a relatively simple high-pressure extraction system using CO2.
Solution Approach 2:
The patent changes the extraction parameters (temperature, pressure, CO2 density) to optimize CBD extraction efficiency. By controlling these parameters, the system achieves high productivity without requiring complex synthesis equipment, as the extraction efficiency is tuned through parameter optimization rather than complex reaction sequences.
3Ease of operation
If CBD is stored or processed without proper stabilization, then it remains accessible for use, but it degrades rapidly when exposed to light, oxygen, and heat
Solution Approach 1:
The patent introduces inert gases (nitrogen or carbon dioxide) as intermediaries that displace oxygen and protect CBD from oxidation. These intermediary gases create a protective atmosphere during storage and processing, preventing degradation while maintaining CBD accessibility.
Solution Approach 2:
The patent stabilizes CBD by storing and processing it in an inert atmosphere of nitrogen or carbon dioxide. This inert environment excludes oxygen and moisture, preventing degradation reactions while keeping the CBD available for use. The inert atmosphere acts as a protective barrier against light, oxygen, and heat-induced degradation.
Data Source
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AI summary
A composition formulated for increased penetration of cannabidiol (CBD) in the skin of an individual upon topical administration of the composition to the skin of the individual, the composition comprising a combination of broccoli seed oil and CBD. A composition for use in increasing penetration of cannabidiol (CBD) in the skin of an individual, wherein said composition comprises a combination of broccoli seed oil and CBD.