CBD-Enhanced Hydroalcoholic Biocide Composition for Extended Skin Disinfection

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Solution Overview

Problem

Current hydroalcoholic hand sanitizer formulations provide only a limited time effect on the skin, requiring frequent reapplication to maintain proper hand sanitization, especially in critical situations like pandemic outbreaks.

Innovation Solution

Incorporating cannabidiol (CBD) into a topical liquid hydroalcoholic composition, which extends the biocidal effect of hydroalcoholic solutions by 1 to 2 hours, comprising 0.01 to 10% w/w CBD, 60 to 90% w/w lower alcohol, 2 to 25% w/w CBD solubilizing agent, and sufficient water, with the solubilizing agent being miscible with the lower alcohol.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If traditional alcohol-based hand sanitizer formulations are used, then effective hand disinfection is achieved, but the duration of biocidal effect is limited to about one minute requiring frequent reapplication

Engineering Contradiction:
Improveduration of biocidal effectVSAvoidfrequency of reapplication
Core Design Contradiction:
Duration of action of moving objectVSLoss of time

Solution Approach 1:

The patent combines CBD (cannabidiol) with traditional hydroalcoholic biocide formulation to create a composite composition. The CBD component extends the duration of biocidal effect from about one minute to at least one or two hours, while the alcohol component maintains the initial rapid disinfection capability. This composite approach allows the formulation to achieve both short-term effectiveness and long-lasting protection.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent modifies the chemical composition parameters of traditional hand sanitizer by adding CBD at specific concentrations (0.01 to 10% w/w) to the hydroalcoholic base. This parameter change transforms the temporal profile of the biocidal effect, extending its duration without compromising the immediate disinfection efficacy provided by the alcohol component.

Inventive Principle:
Principle #35Parameter changes

2Duration of action of moving object

If CBD is added to extend biocidal duration, then long-acting biocide effect is achieved, but formulation complexity increases requiring solubilizing agents

Engineering Contradiction:
Improveduration of biocidal effectVSAvoidformulation complexity
Core Design Contradiction:
Duration of action of moving objectVSDevice complexity

Solution Approach 1:

The patent introduces a CBD solubilizing agent as an intermediary component to enable the incorporation of CBD into the hydroalcoholic formulation. This solubilizing agent facilitates the dissolution and stable integration of CBD, allowing the active ingredient to be effectively delivered without causing formulation instability or separation issues.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The CBD component serves multiple functions in the formulation: it extends the duration of biocidal effect, maintains compatibility with the alcohol-based system, and works synergistically with the solubilizing agent to ensure stable formulation. This multi-functionality reduces the need for additional separate components to achieve duration extension.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The CBD-enhanced hydroalcoholic composition provides a long-acting biocide effect, achieving up to 99.99% reduction in microorganisms on skin surfaces for at least 2 hours, significantly surpassing the duration of traditional alcohol-based sanitizers.

Implementation Method 1

alcohol-based formulations containing 62%-95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses

Methodology Applied
Scientific EffectProtein denaturation:

Implementation Method 2

a CBD solubilizing agent from 2 to 25% w/w and water in a quantity sufficient for the composition to total 100% w/w, wherein the said CBD solubilizing agent is miscible with the lower alcohol

Methodology Applied
Scientific EffectSolvation: Solvation

Data Source

PatentUS20240156698A1Biocide compositions and uses thereof
Publication Date: 2024.05.16 PHARMOTECH SA
  • US20240156698A1 patent drawing

AI summary

The present invention is directed to long lasting topical liquid hydroalcoholic biocide compositions characterised by contents of cannabidiol (CBD) and a CBD solubilizing agent, preferably propylene glycol.