CBD Stability via Pico Carbon Buffering
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Cannabidiol (CBD) is unstable under acidic and alkaline conditions, leading to unwanted chemical side reactions and stability issues in aqueous compositions, which complicates its use in pharmaceutical and beverage formulations, especially for broader population accessibility.
Innovation Solution
An aqueous composition comprising CBD and an alkalizing agent made of pico size carbon particles, which buffers the pH between 7.5 and 9.5, avoiding the use of inorganic or organic bases to maintain stability and prevent side reactions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Stability of the object's composition
If inorganic or organic bases are used to alkalize the composition, then the pH can be adjusted to improve CBD stability, but unwanted chemical side reactions occur and CBD converts to hydroquinones
Solution Approach 1:
Pico size carbon particles are introduced as an intermediary alkalizing agent that buffers the composition to a pH between 7.5 and 9.5 without directly contacting or reacting with CBD molecules. The carbon particles serve as a mediator that provides alkaline conditions while preventing the harmful direct interactions that occur with conventional inorganic or organic bases, thereby eliminating unwanted side reactions and hydroquinones formation.
2Adaptability or versatility
If CBD is dissolved in aqueous solution, then the composition becomes accessible for broader population, but CBD instability under acidic and alkaline conditions leads to degradation
Solution Approach 1:
The pH parameter of the aqueous composition is actively controlled and maintained between 7.5 and 9.5 using pico size carbon particles as a buffering agent. This parameter change from acidic/neutral to alkaline conditions optimizes CBD stability in aqueous solution, preventing degradation while maintaining the desired aqueous formulation for broader accessibility and ease of administration.
3Duration of action of stationary object
If the composition is formulated for long-term storage, then it becomes suitable for pharmaceutical use, but CBD degrades over time under conventional pH conditions
Solution Approach 1:
The pico size carbon particles are pre-incorporated into the aqueous composition to establish a protective alkaline environment (pH 7.5-9.5) before CBD degradation can occur. This preliminary buffering action prevents acidic conditions that would lead to degradation over time, ensuring long-term stability and suitability for pharmaceutical storage and use.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition remains stable for at least 24 months, suitable for human consumption and medical administration, preventing unwanted chemical conversions like hydroquinones formation, and is accessible for all age groups.
Implementation Method 1
an alkalizing agent which comprises pico size carbon particles... present in an amount suitable for buffering the composition to a pH between about 7.5 and 9.5
Implementation Method 2
avoiding the use of inorganic or organic bases to maintain stability and prevent side reactions... preventing unwanted chemical conversions like hydroquinones formation
Data Source
AI summary
An aqueous alkaline composition comprising a cannabinoid which may be cannabidiol (CBD) used alone or in combination with other cannabinoids. An alkalizing agent which comprises pico size carbon particles is present in the composition, in an amount suitable for buffering the composition to a pH between about 7.5 and 9.5. The aqueous alkaline composition is stable and may be used in the preparation of a beverage or a pharmaceutical composition.