Celery Seed Extract Composition for Muscle Weakness and Metabolic Health
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Solution Overview
Problem
Current treatments for muscle weakness-related diseases, such as sarcopenia and muscle dystrophy, often rely on chemical ergogenic aids that come with side effects, and there is a need for a natural alternative that effectively increases muscle mass and strength while addressing metabolic and liver health.
Innovation Solution
A composition comprising celery seed extract as an active ingredient, which can be used in pharmaceutical, food, or feed formulations to prevent or treat muscle weakness, metabolic diseases, and liver diseases by increasing muscle mass, inhibiting muscle tissue lipid content, and improving metabolic parameters.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Strength
If chemical ergogenic aids are used to increase muscle mass, then muscle mass and strength increase, but side effects occur
Solution Approach 1:
The invention changes the chemical composition parameter from synthetic ergogenic aids to natural celery seed extract, maintaining the muscle-building effect while eliminating harmful side effects. The extract contains natural compounds like apiole and phthalides that promote muscle growth without the adverse reactions associated with chemical supplements.
Solution Approach 2:
The invention uses a natural, easily obtainable plant extract (celery seed) instead of complex chemical compounds, making the treatment safer and more accessible. The natural extract can be administered orally without the need for sophisticated delivery systems required for many chemical ergogenic aids.
2Strength
If exercise and diet are used to increase muscle mass, then muscle mass increases, but time and effort are required
Solution Approach 1:
The celery seed extract acts as a biological intermediary that accelerates muscle growth by modulating hormonal pathways (increasing IGF-1, decreasing myostatin) and promoting satellite cell activation. This biochemical mediation achieves muscle anabolism more efficiently than mechanical exercise alone, reducing the time required to achieve similar results.
Solution Approach 2:
The invention changes the physiological parameter of muscle protein synthesis rate by introducing bioactive compounds from celery seed extract that directly stimulate muscle cell proliferation and differentiation, bypassing the need for prolonged mechanical stimulation through exercise.
3Reliability
If muscle mass is increased in obese individuals, then metabolic health improves, but lipid accumulation in muscle tissue may occur
Solution Approach 1:
The invention exhibits local quality effects by selectively influencing lipid metabolism in different tissues. The celery seed extract promotes lipid oxidation and prevents lipogenesis specifically in muscle tissue while having different effects in adipose tissue, thereby increasing muscle mass without causing intramuscular lipid accumulation that would compromise muscle quality.
Solution Approach 2:
The invention changes the metabolic parameter of lipid metabolism by activating pathways that promote fatty acid oxidation and inhibit lipid synthesis in muscle cells. This is achieved through compounds in the extract that modulate enzymes involved in lipid metabolism, ensuring that muscle growth occurs without concurrent lipid accumulation.
Data Source
AI summary
The present invention relates to a composition, for preventing, relieving, or treating a muscle weakness-related disease, comprising a celery seed extract. The celery seed extract according to the present invention causes a few or no side effects by using a natural product, may increase muscle mass and muscle strength to not only prevent muscle weakness but also inhibit weight gain and body fat increase, and may reduce serum lipid profiles and hepatotoxicity markers (GOT and GPT), and thus is expected to be utilized for preventing, relieving, or treating muscle weakness-related diseases, metabolic diseases, liver diseases, or the like.