Cell Autophagy Cosmetic Composition for Damaged Skin Repair

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Solution Overview

Problem

Existing cosmetics fail to repair or enhance cell autophagy, leading to impaired skin health due to damaged skin cells and a vicious cycle of oxidative damage.

Innovation Solution

A cell autophagy composition comprising collagen, yeast fermentation product extract, acetyl hexapeptide-8, palmitoyl hexapeptide-12, dipeptide-15, tripeptide-1, dipeptide-1, 1,2-hexanediol, and ethylhexylglycerin, which synergistically enhance autophagy and restore skin health.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If traditional cosmetics focus on hydration and nourishment, then skin moisture and nutrition are improved, but cell autophagy function cannot be repaired or enhanced

Engineering Contradiction:
Improveskin moisture and nutritionVSAvoidcell autophagy function
Core Design Contradiction:
Quantity of substanceVSReliability

Solution Approach 1:

The patent introduces specific peptide components (acetyl hexapeptide-8, palmitoyl hexapeptide-12, dipeptide-15, tripeptide-1, dipeptide-1) and yeast fermentation product extract that fundamentally change the functional parameters of the cosmetic formulation. These components specifically target and enhance cell autophagy pathways, transforming the cosmetic from merely providing hydration to actively repairing cellular self-cleaning functions while maintaining moisture levels.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite cosmetic formulation that combines traditional hydration ingredients with novel autophagy-enhancing components including multiple peptides and yeast fermentation products. This composite approach allows the cosmetic to simultaneously provide moisture, nourishment, and cellular repair functions that were previously unachievable with single-function ingredients.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If skin cells are damaged by stress, environment, diet, and cosmetics, then skin health deteriorates, but existing cosmetics cannot clean up damaged cells

Engineering Contradiction:
Improveskin cell damageVSAvoidcosmetic repair capability
Core Design Contradiction:
Object-affected harmful factorsVSEase of manufacture

Solution Approach 1:

The patent employs components that activate the skin cells' own autophagy mechanisms, enabling the cells to self-repair and self-cleanse damaged components. The peptides and yeast fermentation products stimulate the cell's intrinsic ability to degrade and recycle damaged proteins and organelles through lysosomal pathways, allowing the skin to repair itself rather than relying on external replacement of damaged cells.

Inventive Principle:
Principle #25Self-service

3Duration of action of stationary object

If skin cells enter a vicious circle of oxidative damage, then skin condition worsens over time, but traditional cosmetics cannot break this cycle

Engineering Contradiction:
Improveskin condition stabilityVSAvoidoxidative damage
Core Design Contradiction:
Duration of action of stationary objectVSObject-generated harmful factors

Solution Approach 1:

The patent implements preliminary protective action by enhancing the skin cells' autophagy capacity before oxidative damage can accumulate. The active components prepare the cellular defense systems in advance, enabling cells to more effectively handle and eliminate oxidative stressors before they cause significant damage, thereby preventing the vicious cycle from establishing in the first place.

Inventive Principle:
Principle #9Preliminary anti-action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively repairs damaged skin cells, enhances autophagy, and maintains a healthy skin environment by promoting collagen synthesis and waste removal, ensuring safe and effective use in cosmetic products.

Implementation Method 1

The yeast fermentation product extract is rich in various nutrients required for the growth of skin cells, including substances such as amino acids and polysaccharides

Methodology Applied
Scientific EffectFermentation: Fermentation

Data Source

PatentEP4591848A1Cell autophagy composition and preparation method and application thereof
Publication Date: 2025.07.30 SHAANXI HUIKANG BIO TECH CO LTD
  • EP4591848A1 patent drawingFigure 1~2
  • EP4591848A1 patent drawingFigure 3
  • EP4591848A1 patent drawing

AI summary

The present disclosure discloses a cell autophagy composition. The cell autophagy composition having a composition of, by mass percent: 0.05% to 0.5% of collagen; 0.5% to 3% of a yeast fermentation product extract; 0.01% to 0.5% of acetyl hexapeptide-8; 0.01% to 0.5% of palmitoyl hexapeptide-12; 0.01% to 0.5% of dipeptide-15; 0.1% to 2% of tripeptide-1; 0.01% to 0.5% of dipeptide-1; 5% to 10% of 1,2-hexanediol; and 0.05% to 0.5% of ethylhexylglycerin, with the remainder being water. The present disclosure also discloses a preparation method and an application of the cell autophagy composition. According to the cell autophagy composition of the present disclosure, the problem that existing cosmetics cannot repair or enhance the cell autophagy effect can be addressed. The cell autophagy composition of the present disclosure is simple in formulation, safe, and remarkable in effect, and can be directly used for developing various cosmetic products.