Cell-Based Meat via Extinct Species DNA Expression

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Solution Overview

Problem

The existing market for conventional food products struggles to meet growing demand, and conventional meat production faces issues such as low caloric conversion, microbial contamination, veterinary and zoonotic diseases, resource requirements, and environmental pollutants, prompting the need for alternative, sustainable solutions.

Innovation Solution

Development of in vitro produced cell-based products that include proteins from exotic, endangered, and extinct species, achieved by cloning and expressing DNA constructs in host animal cells or forming syncytial heterokaryons to induce expression of ancestral genes, allowing for the creation of novel nutrition and organoleptic profiles without the need for animal slaughter.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If conventional meat production is used to meet growing demand, then food supply increases, but environmental pollutants, microbial contamination, and veterinary diseases increase

Engineering Contradiction:
Improvefood supplyVSAvoidmicrobial contamination and environmental pollutants
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent creates cell-based meat products by copying the cellular structure and protein composition of conventional meat through in vitro cultivation. Host cells are genetically modified to express proteins from exotic, endangered, or extinct species, producing a copy of the desired meat product without requiring actual animal slaughter or conventional farming operations that cause environmental pollution and microbial contamination.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent uses host cells as an intermediary system to produce proteins from species that would otherwise require harvesting or poaching. The host cells serve as a mediator that can be cultured in controlled environments, eliminating the need for direct contact with wild or endangered species while still producing the desired protein products.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If DNA constructs from extinct species are cloned and expressed in host cells, then unique nutrition and organoleptic profiles are created, but device complexity and manufacturing difficulty increase

Engineering Contradiction:
Improvenutrition and organoleptic profilesVSAvoidgenomic engineering mechanisms
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent employs a universal host cell system that can express proteins from multiple different species, including extinct, exotic, and endangered species. The same host cell infrastructure and genomic engineering mechanisms can be used to produce proteins from dinosaurs, mammoths, or any other species with available genetic information, making the system highly versatile and adaptable.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent performs preliminary genomic engineering of host cells to establish stable expression systems before producing the final protein products. DNA constructs are prepared, vectors are designed, and host cells are pre-modified with the necessary genetic machinery to ensure efficient protein expression, simplifying the overall manufacturing process.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides sustainable, contamination-free, and nutritionally enhanced cell-based products with unique profiles, addressing the limitations of conventional meat production and offering extended shelf life and reduced environmental impact.

Implementation Method 1

DNA constructs encoding for proteins from extinct, exotic, or endangered species may be cloned and expressed in agriculturally or nutritionally-relevant host animal cells. Alternatively, the host cell may come from yeast or bacteria.

Methodology Applied
Scientific EffectCloning and expression:

Implementation Method 2

the DNA constructs derived from the extinct, exotic, or endangered species may be physically integrated into the host animal cell genome via various genomic engineering mechanisms prior to expression

Methodology Applied
Scientific EffectGenomic integration:

Implementation Method 3

cells from distinct species related by a distant, common ancestor (e.g., an extinct, exotic, or endangered ancestral species) may be fused together to form syncytial heterokaryons. Formation of these syncytial heterokaryons may induce expression of genes from the common ancestral species that were silenced over the course of evolution.

Methodology Applied
Scientific EffectCell fusion:

Data Source

PatentUS20220333081A1Generation of cell-based products for consumption that comprise proteins from exotic, endangered, and extinct species
Publication Date: 2022.10.20 THE UPSIDE GROUP INC
  • US20220333081A1 patent drawing
  • US20220333081A1 patent drawing
  • US20220333081A1 patent drawing

AI summary

The present disclosure relates to methods of preparing cell-based products for consumption that comprise proteins from exotic, endangered, and extinct species, as well as cell-based products for consumption.