Cell Counting Device with Thickness-Setting Pressing Table
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Solution Overview
Problem
Existing cell counting devices face accuracy issues due to variations in container film thickness, requiring labor-intensive adjustments and potentially leading to contamination and reduced reliability when counting cells in culture containers.
Innovation Solution
A counting device with a flexible container and a pressing table that adjusts the container's thickness using thickness-setting members, allowing for accurate cell counting without considering film thickness variations, thereby improving measurement accuracy and workability.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If the thickness of the culture container is adjusted to a prescribed thickness, then the number of cells in the measurement range can be controlled to fall within a prescribed range, but the measurement accuracy is lowered when film thickness varies
Solution Approach 1:
A pressing table with thickness-setting members is introduced as an intermediary device between the culture container and the measurement system. This pressing table standardizes the liquid layer thickness independently of the container's film thickness variations, allowing accurate cell density measurements regardless of container differences
Solution Approach 2:
The invention changes the physical parameter of liquid layer thickness to a standardized value using the pressing table mechanism. By controlling the thickness parameter separately from container film thickness, the system achieves consistent measurement conditions across different containers
2Ease of operation
If the thickness-adjusting means adjusts the measurement region to a prescribed thickness, then cell counting becomes feasible, but labor required for adjustment increases and reliability decreases
Solution Approach 1:
The pressing table with thickness-setting members automatically standardizes the liquid layer thickness without requiring manual adjustment for each container. The system self-adjusts to the correct thickness parameter, eliminating the need for skilled operators to manually compensate for film thickness variations
Solution Approach 2:
The thickness-setting members are pre-configured with standard thickness values. Before measurement, the pressing table is prepared with the appropriate thickness setting, so that when a container is placed on it, the correct liquid layer thickness is automatically achieved without requiring real-time adjustment
3Adaptability or versatility
If containers with varying film thickness are used, then adaptability increases, but the accuracy of cell density calculation is lowered
Solution Approach 1:
The invention decouples the measurement parameter (liquid layer thickness) from the container parameter (film thickness). By using the pressing table to control liquid layer thickness independently, the system can accommodate containers with varying film thickness while maintaining consistent and accurate cell density measurements
Data Source
AI summary
A counting device counts the number of counting objects in liquid in a flexible container. The counting device includes a mounting table on which the container is mounted and a pressing table arranged opposite to a container-arranged side of the mounting table. The mounting table and the pressing table move relatively in a direction of sandwiching the container, and a light-passing hole facing a surface of the container is provided in at least one of the mounting table and the pressing table. The pressing table includes one or more thickness-setting members that sandwich the container between the pressing table and the mounting table in a periphery of the light-passing hole and on the side opposite to the container in a protruding manner.