Medical Image Cell Matrix Classification With Spatial Context

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Solution Overview

Problem

Existing methods for analyzing medical image data face challenges such as large data sizes, loss of global arrangement and interaction details, and human bias in feature selection, leading to inefficiencies and inaccuracies in automated processing.

Innovation Solution

A method involving the construction of a matrix with intensity values representing cell characteristics, allowing for efficient processing and preservation of spatial and interaction information, followed by deep learning techniques to enhance feature extraction and classification.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual interpretation of medical images is used, then diagnostic accuracy is maintained, but time consumption increases and scalability is limited

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidanalysis speed
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent creates a digital representation (matrix) that copies and transforms the essential features of the medical image into a computationally efficient format. This matrix representation preserves the diagnostic information while enabling rapid automated processing, thus maintaining accuracy while improving speed and scalability.

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent transforms the image data from its original pixel-based representation into a matrix of intensity values representing cell characteristics. This parameter transformation enables the data to be processed more efficiently by automated systems while maintaining the essential diagnostic information needed for accurate analysis.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If deep learning processes individual small-size patches, then detail capture is improved, but global arrangement information is lost

Engineering Contradiction:
Improvefeature extraction accuracyVSAvoidglobal arrangement information
Core Design Contradiction:
Measurement precisionVSLoss of information

Solution Approach 1:

The patent segments the medical image into a matrix where each element corresponds to a spatial area, allowing localized feature extraction while maintaining global context through the overall matrix structure. This segmentation enables detailed analysis of specific regions without losing the global arrangement information encoded in the matrix dimensions and spatial relationships.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent transforms the 2D image into a matrix representation that adds an intensity dimension, creating a three-dimensional data structure (spatial x intensity). This dimensional transformation allows simultaneous capture of local features, global arrangement, and intensity information, resolving the contradiction between detailed patch analysis and global context preservation.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Device complexity

If hand-crafted metrics are selected for image analysis, then feature extraction is simplified, but bias increases and problem-relevance decreases

Engineering Contradiction:
Improvefeature extraction complexityVSAvoidanalysis objectivity
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent enables the system to automatically extract and represent cell characteristics without requiring manual selection of hand-crafted metrics. The matrix representation is generated through automated processing that identifies and encodes relevant features, eliminating human bias in feature selection while maintaining computational efficiency.

Inventive Principle:
Principle #25Self-service

4Measurement precision

If original high-resolution medical images are processed directly, then detail preservation is maintained, but processing efficiency decreases

Engineering Contradiction:
Improvespatial information preservationVSAvoidprocessing efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent extracts the essential diagnostic information from the high-resolution medical image and represents it in a compressed matrix format. This extraction process retains the critical spatial and intensity information while significantly reducing the data size and processing requirements, thus improving efficiency without sacrificing diagnostic precision.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentEP4664396A1Systems and methods for analysing medical image data
Publication Date: 2025.12.17 SPATIALX DIAGNOSTICS LTD
  • EP4664396A1 patent drawingFigure 1
  • EP4664396A1 patent drawingFigure 2(a)~2(d)
  • EP4664396A1 patent drawingFigure 2(e)

AI summary

A method for analysing medical image data, the method comprising steps of: receiving medical image data comprising an image; using predetermined criteria to identify one or more subsets of cells in the image by identifying one or more characteristics of the cells; providing a matrix corresponding to the image comprising a plurality of elements, wherein each element corresponds to a spatial area in the image; populating the matrix by assigning an intensity value to each element in the matrix, the intensity value representing an intensity of a feature of the subset of identified cells in the corresponding area in the image, and processing the populated matrix to identify a classification for the medical image data.