Cell Rotation Apparatus for Automated Image Capture
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Solution Overview
Problem
Current technologies for evaluating cell quality based on cell images lack accuracy and rely heavily on manual operations and subjective evaluations.
Innovation Solution
An apparatus that includes an accommodation unit for cells and liquid, a rotation unit to rotate cells automatically by producing fluid flows, and a rotation controller unit to control the rotation direction and amount, allowing for precise image capture and objective evaluation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If manual operations are used to rotate and observe cells, then flexibility in observation is maintained, but evaluation accuracy is limited by subjective errors and operational inconsistency
Solution Approach 1:
The system enables automatic cell rotation and observation without manual intervention. The rotation unit automatically rotates the cell holder, and the image capturing unit automatically captures images from multiple angles, eliminating the need for manual operations while maintaining observation flexibility.
Solution Approach 2:
The patent replaces manual mechanical operations with an automated control system. The rotation controller unit coordinates the rotation unit and image capturing unit through electronic control, substituting human manual operations with an automated mechanical and control system that improves precision and eliminates subjective errors.
2Adaptability or versatility
If cells are observed from limited angles, then observation simplicity is maintained, but three-dimensional evaluation capability is lost
Solution Approach 1:
The system dynamically rotates the cell holder to multiple predetermined angles during observation. The rotation unit changes the orientation of the cell holder according to a predetermined rotation angle, enabling the image capturing unit to capture images from multiple angles and reconstruct three-dimensional cell structures.
Solution Approach 2:
The observation process is segmented into multiple discrete angular positions. The rotation unit rotates the cell holder to specific predetermined angles, and the image capturing unit captures images at each position. This segmentation of the observation process into discrete angular steps enables comprehensive three-dimensional evaluation while maintaining systematic control.
3Productivity
If rapid cell rotation is implemented, then observation efficiency is improved, but control precision over rotation amount is reduced
Solution Approach 1:
The system incorporates feedback control where the rotation controller unit monitors and adjusts the rotation based on predetermined rotation angles. The controller ensures that the cell holder rotates to the exact predetermined angles required for observation, maintaining precision while enabling rapid sequential rotation through automated control.
Solution Approach 2:
The rotation is performed in periodic steps at predetermined angles rather than continuous rotation. The rotation unit rotates the cell holder to specific angular positions, pauses for image capture, then rotates to the next position. This periodic action enables both speed (through automated sequencing) and precision (through controlled angular positioning).
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The apparatus enhances the accuracy of cell evaluation by enabling precise rotation and image capture, reducing manual intervention and subjective errors, and allowing for three-dimensional observation and evaluation of cells.
Implementation Method 1
a rotation unit that produces a flow in the liquid in the accommodation unit to rotate the cell
Data Source
AI summary
An apparatus includes: an accommodation unit capable of accommodating a cell and liquid; and a rotation unit that produces a flow in the liquid in the accommodation unit to rotate the cell. The apparatus further includes a rotation controller unit that detects a rotation amount input from an input device, and controls the flow of the liquid produced by each of the output ports on a basis of the input rotation amount to control a rotation amount of the cell.