Cell Therapy Control System Automation

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Solution Overview

Problem

The manual transfer of cell solutions in cell therapy processes is inefficient and prone to contamination due to the independence of cell processing devices, leading to suboptimal cell product quality.

Innovation Solution

A control system for cell therapy comprising a cell processing module, an auxiliary connection module, and a cell culture module connected in sequence, with a processor controlling the modules to create a closed environment for automatic transfer and storage of cell solutions, reducing manual handling and contamination risks.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If manual transfer method is used to transfer cell solution between independent cell processing devices, then operational flexibility is maintained, but transfer efficiency is low and contamination risk increases

Engineering Contradiction:
Improvetransfer efficiencyVSAvoidsystem integration complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent merges multiple independent cell processing devices into an integrated system through a unified control unit and common cell solution storage system. The control unit coordinates operations across different devices, enabling automated cell solution transfer without manual intervention, thereby improving transfer efficiency while reducing contamination risk

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent introduces a control unit as an intermediary component that manages the transfer of cell solutions between independent processing devices. This intermediary coordinates the transfer process automatically, eliminating the need for manual handling and maintaining system flexibility while improving operational efficiency

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If frequent manual transfer of cell solution is performed, then adaptability to different processing steps is maintained, but contamination risk increases

Engineering Contradiction:
Improvecell product qualityVSAvoidoperational simplicity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent implements self-service functionality where the system automatically transfers cell solutions between processing devices based on programmed instructions. The control unit monitors and executes transfer operations without requiring manual intervention, thereby maintaining adaptability to different processing steps while reducing contamination risk from frequent manual handling

Inventive Principle:
Principle #25Self-service

3Adaptability or versatility

If independent cell processing devices are used, then operational flexibility is maintained, but the need for frequent manual transfer increases

Engineering Contradiction:
Improveprocess configuration flexibilityVSAvoidtransfer time
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent implements preliminary action by pre-programming the control unit with transfer instructions and establishing a common cell solution storage system before processing begins. This allows the system to automatically execute transfer operations between independent devices without manual intervention, maintaining process configuration flexibility while eliminating transfer time losses associated with frequent manual handling

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS20250011705A1Control system for cell therapy and control method therefor
Publication Date: 2025.01.09 NANJING GENSCRIPT BIOTECH CO LTD
  • US20250011705A1 patent drawing
  • US20250011705A1 patent drawing
  • US20250011705A1 patent drawing

AI summary

A control system for cell therapy and a control method therefor. The control system may comprise a cell processing module, an auxiliary connection module, and a cell culture module which are connected in sequence; and a processor which is in communication connection with the cell processing module, the auxiliary connection module and the cell culture module, wherein the processor controls the auxiliary connection module to temporarily store a cell solution of the cell processing module and to transfer the temporarily stored cell solution to the cell culture module.