Noble Metal Cannabinoid Comestibles with Cellular Microencapsulation
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing methods face challenges in solubilizing and delivering hydrophobic compounds like cannabinoids in aqueous solutions, leading to inconsistent dosing, poor absorption, and difficulty in formulation due to their hydrophobic nature, which affects bioavailability and distribution.
Innovation Solution
A method involving microencapsulation using cellular materials like Spirulina, which disrupts the cellular material to encapsulate hydrophobic compounds without synthetic detergents, forming a stable, water-soluble finished product by combining the encapsulated mixture with a comestible noble metal.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of manufacture
If hydrophobic compounds like cannabinoids are directly dissolved in aqueous solutions, then the formulation process becomes simple, but the solubility and uniformity of the compounds deteriorate
Solution Approach 1:
The patent uses natural cellular materials (such as Spirulina, yeast, or bacterial cells) as intermediary carriers to encapsulate hydrophobic cannabinoids. These cellular materials have both hydrophilic outer surfaces for aqueous solubility and hydrophobic interior regions that can accommodate cannabinoids, thereby mediating between the incompatible aqueous and hydrophobic phases without requiring synthetic detergents or surfactants.
Solution Approach 2:
The invention creates composite structures where hydrophobic cannabinoids are embedded within natural cellular material matrices. These composite particles combine the properties of both components: the cellular material provides water solubility and stability, while the embedded cannabinoids provide the desired pharmacological effects, achieving both ease of formulation and compositional stability.
2Stability of the object's composition
If synthetic detergents are used to solubilize hydrophobic compounds, then the solubility improves, but the product safety and naturalness deteriorate
Solution Approach 1:
The patent employs readily available natural cellular materials (Spirulina, yeast, bacteria) that can be easily cultivated, disrupted, and discarded after use. These materials serve as temporary solubilizing agents that are broken down during processing, leaving no persistent synthetic residues in the final product, thus maintaining safety and naturalness while achieving solubility.
Solution Approach 2:
The natural cellular materials inherently possess both hydrophilic and hydrophobic properties that enable them to self-organize and encapsulate cannabinoids without requiring external synthetic surfactants. The cellular structures naturally provide the solubilizing function through their own biochemical composition, eliminating the need for harmful synthetic additives.
3Reliability
If hydrophobic compounds are encapsulated using natural cellular materials, then the bioavailability and uniformity improve, but the manufacturing complexity increases
Solution Approach 1:
The manufacturing process is divided into distinct modular steps: (1) preparation of cellular material suspension, (2) mixing with cannabinoids, (3) ultrasonic disruption to release encapsulated compounds, and (4) filtration. Each step is independently optimized and can be performed with standard equipment, making the overall complex process manageable and scalable while ensuring consistent bioavailability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The method achieves high uniformity and stability of hydrophobic compounds, allowing for consistent dosing and improved bioavailability by forming a water-soluble, stable product suitable for edible and topical applications.
Implementation Method 1
The blended aqueous solution is ultrasonicated to at least partially liberate proteins of the Spirulina
Implementation Method 2
The intermediate mixture is ultrasonicated to form a first mixture including the Cannabis extract material encapsulated by the Spirulina
Implementation Method 3
The first mixture can then be further processed, such as via sonication and/or multiple sonication steps... which can then be dehydrated to form a dehydrated sheet
Data Source
AI summary
A method for the micro-encapsulation of terpenes, lipids, sterols, antioxidants, cannabinoids and/or other hydrophobic compounds includes providing an extract material and preparing an aqueous solution including a cellular material. A disruption of the aqueous solution is performed, to at least partially liberate proteins of the cellular material. The extract material and the disrupted aqueous solution are combined to form an intermediate mixture. The intermediate mixture is disrupted to form an encapsulated mixture, and a pH of the encapsulated mixture is reduced. The encapsulated mixture is then dried and combined with a comestible noble metal, to form a finished product.