Centrifugal Separation Container With Concave Interface For Low Specific Gravity Recovery
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Solution Overview
Problem
Existing centrifugal separation containers face challenges in efficiently recovering low specific gravity components due to slow release rates and increased manufacturing costs associated with complex designs, such as capillary phenomenon induction and hydrophilic/hydrophobic region formation.
Innovation Solution
A centrifugal separation container with an inclined inner wall and a concave portion at the interface between the specimen and air, facilitating the release of low specific gravity components by allowing them to be pulled towards the concave portion, which can be easily formed during manufacturing, thereby simplifying the process and reducing costs.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If capillary phenomenon inducing structures are formed on the inner wall surface to facilitate release of low specific gravity component, then recovery efficiency is improved, but manufacturing complexity and cost increase
Solution Approach 1:
The patent applies parameter changes by modifying the surface properties of the inner wall through hydrophilic treatment in specific regions. Instead of complex capillary structures, the invention changes the wettability parameter of the surface to create hydrophilic regions that facilitate release of the low specific gravity component, thereby improving recovery efficiency while maintaining simple manufacturing processes
Solution Approach 2:
The patent implements local quality by creating hydrophilic regions at specific locations on the inner wall surface where the low specific gravity component contacts during centrifugal separation. This localized modification of surface properties enables targeted facilitation of component release without requiring complex structures throughout the entire container, thus improving recovery efficiency while keeping manufacturing simple
2Productivity
If hydrophilic region and hydrophobic region are formed on the inner wall surface to facilitate flow and release, then recovery efficiency is improved, but manufacturing processes become complicated
Solution Approach 1:
The patent applies parameter changes by modifying the surface energy characteristics of the inner wall through selective hydrophilic treatment. This creates regions with different wettability parameters that guide the flow and release of the low specific gravity component, achieving improved recovery efficiency through a manufacturing process that involves only simple coating or treatment steps rather than complex multi-step processes
Solution Approach 2:
The patent employs a disposable container design where the hydrophilic regions are formed through simple, cost-effective surface treatment that can be applied during manufacturing. The container is designed for single use, eliminating the need for complex cleaning or reprocessing, thus maintaining ease of manufacture while achieving improved recovery efficiency
3Reliability
If solvent is applied to the inner wall for prevention of hemolysis, then specimen integrity is improved, but release of low specific gravity component becomes more difficult
Solution Approach 1:
The patent resolves this contradiction by applying solvent treatment selectively to specific regions of the inner wall where specimen integrity is most critical, while leaving other regions with hydrophilic properties that facilitate release of the low specific gravity component. This localized differentiation of surface properties maintains specimen integrity in hemolysis-prone areas while enabling efficient component release in other areas
Solution Approach 2:
The patent segments the inner wall surface into distinct functional regions: areas treated with solvent for hemolysis prevention and areas with hydrophilic properties for component release facilitation. This segmentation allows each region to perform its specific function optimally, maintaining specimen integrity where needed while enabling efficient release where required
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The container efficiently recovers centrifugally separated components by allowing the low specific gravity component to be released first from the layer structure body, improving recovery efficiency and reducing manufacturing complexity and costs.
Implementation Method 1
components having a low specific gravity in the respective components of the specimen are separated first by a centrifugal force, which is caused by the rotation of the container
Implementation Method 2
JP2001-239185A discloses a method of facilitating the release of a low specific gravity component from the layer structure body by inducing the capillary phenomenon of a low specific gravity component using a centrifugal separation container that includes capillary phenomenon inducing structures formed on an inner wall surface of a storage portion thereof
Data Source
AI summary
A storage portion forming a storage space 10, includes an inclined inner wall portion 20 that is connected to a base portion so that the diameter of the inclined inner wall portion gradually decreases; a concave portion 22 is formed at a part of the inclined inner wall portion; and the concave portion 22 includes a concave portion side surface 22b that is connected to a concave portion bottom surface 22a. The concave portion 22 is formed at a position, where the concave portion crosses an interface S between the specimen centrifuged during rotation and air, in a radial direction with respect to the central axis; and the maximum width of the concave portion 22 in a circumferential direction around the central axis is included in a range of 2 mm to a length of 20% of the whole circumference.


