Ceramic-Sonicated Functional Water for Aquaporin Cell Penetration

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Solution Overview

Problem

Existing functional waters, such as alkaline and hydrogen-rich water, do not effectively address the need for enhanced cell-penetrating capability and health benefits related to hydration, metabolic waste removal, and oxidative stress reduction.

Innovation Solution

A method involving the preparation of aquaporin water by sonicating ceramic, such as Tadanoumi ceramic, in water to induce structural changes in water molecules, increasing the H—O—H bond angle to 120°, and applying the water through a ceramic column to enhance cell-penetrating capability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional functional water (alkaline water, hydrogen-rich water) is used, then basic hydration needs are met, but cell-penetrating capability and health benefits are insufficient

Engineering Contradiction:
Improvecell-penetrating capabilityVSAvoidhealth benefits range
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies parameter changes by modifying the H-O-H bond angle of water molecules from the conventional 104.45° to approximately 120° through ceramic sonication. This structural parameter change enables the water to better fit aquaporin channels, significantly enhancing cell-penetrating capability and enabling multiple health benefits including improved hydration, metabolic waste removal, and oxidative stress reduction

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses mechanical vibration through sonication of ceramic materials in water to induce structural changes in water molecules. The ultrasonic vibration energy transforms the water molecular structure, creating aquaporin-friendly water that can effectively penetrate cell membranes while providing comprehensive health benefits

Inventive Principle:
Principle #18Mechanical vibration

2Speed

If water molecules maintain regular H-O-H bond angle of 104.45°, then natural water properties are preserved, but penetration efficiency through aquaporins is limited

Engineering Contradiction:
Improvemetabolic waste removal speedVSAvoidwater molecular structure
Core Design Contradiction:
SpeedVSStability of the object's composition

Solution Approach 1:

The patent deliberately changes the H-O-H bond angle parameter from 104.45° to approximately 120° to optimize water molecule fit within aquaporin channels. This parameter change increases penetration speed and metabolic waste removal efficiency while maintaining water's fundamental properties through controlled structural modification

Inventive Principle:
Principle #35Parameter changes

3Adaptability or versatility

If functional water is enhanced with supplements such as vitamins and minerals, then additional health benefits are provided, but cell penetration efficiency is compromised

Engineering Contradiction:
Improvehealth functional benefitsVSAvoidcell-penetrating capability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The patent prioritizes changing the fundamental water molecular structure (H-O-H bond angle to 120°) to ensure optimal cell penetration. This structural modification takes precedence over supplement addition, as it directly enables effective aquaporin channel penetration while providing core health benefits including hydration, waste removal, and oxidative stress reduction

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The aquaporin water demonstrates improved cell viability, oxidative injury protection, telomere preservation, and anti-inflammatory effects, facilitating faster metabolic waste removal, particularly hydrogen peroxide, through aquaporins.

Implementation Method 1

sonicating the ceramic in the water at predetermined sonication power at the predetermined temperature for a second predetermined period of time

Methodology Applied
Scientific EffectSonication: Ultrasonic Vibration

Implementation Method 2

The ceramic induces structural change of at least some water molecules of the water. In one embodiment, water molecules of the aquaporin water have a H—O—H bond angle α, and a H—O—H bond angle α1 of the changed water molecules is greater than a regular H—O—H bond angle α0 of the water molecules of the water prior to being processed

Methodology Applied
Scientific EffectStructural change of water molecules:

Implementation Method 3

facilitating faster metabolic waste removal, particularly hydrogen peroxide, through aquaporins

Methodology Applied
Scientific EffectAquaporin-mediated transport: Permeation

Data Source

PatentUS20250223195A1Methods of making and testing functional water with enhanced cell-penetrating capability and applications thereof
Publication Date: 2025.07.10 GOLDEN ALLY LIFETECH GRP CO LTD
  • US20250223195A1 patent drawing
  • US20250223195A1 patent drawing
  • US20250223195A1 patent drawing

AI summary

A method of making functional water with enhanced cell-penetrating capability is provided. The method includes preparing a ceramic by melting natural clay and iron-containing sand, immerging the ceramic in water with a predetermined ceramic-to-water weight ratio at a predetermined temperature for a first predetermined period of time, and sonicating the ceramic in the water at predetermined sonication power at the predetermined temperature for a second predetermined period of time. The water being sonicated is then applied to flow through a column filled with the ceramic at the predetermined temperature to obtain the functional water. The water flows through the column with a predetermined water flow-to-ceramic weight ratio, or with a third predetermined time for a unit volume of the water passing through a unit weight of the ceramic. The ceramic induces structural change of at least some water molecules of the water.