Ceramide Wax Solidified Melt for Stable Cosmetic Formulations

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Solution Overview

Problem

Ceramides have low solubility and a strong tendency to recrystallization, making it difficult to stably incorporate them into cosmetic formulations, particularly into oil-in-water emulsions, and require high temperatures for dissolution, which can damage temperature-sensitive ingredients and limit storage stability.

Innovation Solution

A method involving melting a mixture of wax and ceramide, cooling it to form a solidified melt, and then incorporating this melt into an oil-containing formulation, which lowers the dissolution temperature of ceramides in oils, allowing for energy-efficient preparation and stable storage.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If ceramides are incorporated into cosmetic formulations using conventional methods, then they can be included in the formulation, but their low solubility and strong tendency to recrystallization cause instability and require high dissolution temperatures

Engineering Contradiction:
Improveformulation stabilityVSAvoiddissolution temperature
Core Design Contradiction:
Stability of the object's compositionVSTemperature

Solution Approach 1:

The patent changes the physical-chemical parameters of ceramides by converting them into derivative compounds with modified molecular structures. These derivatives have improved solubility properties and reduced recrystallization tendency, allowing dissolution at lower temperatures while maintaining formulation stability. The parameter change involves modifying the chemical structure rather than changing processing conditions.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates composite material systems by combining ceramide derivatives with specific excipients and formulation components. This composite approach enhances the solubility and stability of ceramides in cosmetic formulations, allowing for stable incorporation without requiring high dissolution temperatures. The composite nature of the formulation prevents recrystallization issues.

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If high temperatures are used to dissolve ceramides, then they can be incorporated into the formulation, but temperature-sensitive ingredients are damaged

Engineering Contradiction:
Improveincorporation capabilityVSAvoidthermal damage to ingredients
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

By changing the chemical parameters of ceramides into derivatives with improved solubility characteristics, the patent enables incorporation at lower temperatures. This parameter change directly addresses the harmful thermal effects on temperature-sensitive ingredients while maintaining ease of manufacture through the enhanced solubility of the derivative compounds.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If conventional delivery forms are used for ceramides, then they can be supplied in cosmetic formulations, but stable incorporation is difficult due to low solubility and recrystallization tendency

Engineering Contradiction:
Improvestable incorporationVSAvoiddelivery form complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies parameter changes by transforming ceramides into derivative compounds with fundamentally different solubility and crystallization properties. This chemical parameter change provides reliable stable incorporation without requiring complex delivery systems, simplifying the overall formulation approach while achieving the desired reliability.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables the incorporation of ceramides into formulations at lower temperatures, improving storage stability and tolerance to freeze-thaw cycles, and allows for the use of temperature-sensitive ingredients while reducing processing temperatures.

Implementation Method 1

A) melting a mixture comprising at least one wax and at least one ceramide

Methodology Applied
Scientific EffectMelting: Melting

Implementation Method 2

B) cooling the molten mixture to obtain a solidified melt comprising the at least one wax and the at least one ceramide

Methodology Applied
Scientific EffectCooling: Cooling

Data Source

PatentUS11000458B2Method and product for producing formulations containing ceramide
Publication Date: 2021.05.11 EVONIK OPERATIONS GMBH

AI summary

The subject matter of the invention is a method for producing a formulation containing ceramide, comprising the method steps:A) Melting a mixture containing at least one wax and at least one ceramide,B) Cooling the melted mixture to obtain a solidified melt containing the at least one wax and the at least one ceramide,C) Incorporating the solidified melt into a formulation containing oil.The invention also relates to the solidified melt of the aforementioned mixture.