Cervical Tissue Relaxation for Minimally Invasive Insemination
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Solution Overview
Problem
Current reproductive technologies, such as laparoscopic insemination, often cause damage, infection, and low conception rates due to the complex anatomy of reproductive tracts, particularly in small ruminants, and transcervical methods are not effective enough, leading to poor breeding outcomes and potential infertility.
Innovation Solution
A non-sedative, minimally invasive method using a natural substance-based treatment applied topically to relax reproductive tissues, such as the cervix, to facilitate safe passage of instruments without causing harm, combined with a delivery mechanism that positions the animal for optimal treatment application.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If laparoscopic insemination is used to ensure reliable breeding in small ruminants, then breeding success is improved, but tissue damage, infection risk, and animal trauma increase
Solution Approach 1:
The patent applies preliminary action by administering cervical ripening agents (such as prostaglandins or natural substances like papaya latex) before the insemination procedure to soften and dilate the cervix. This preliminary treatment allows subsequent transcervical insemination to proceed without the need for invasive laparoscopic surgery, thereby achieving breeding success while avoiding tissue damage and animal trauma associated with surgical intervention
Solution Approach 2:
The patent replaces the mechanical surgical system (laparoscope, surgical instruments, anesthesia) with a biochemical system (cervical ripening agents, transcervical catheters). By using pharmacological or natural substances to prepare the cervix, the method substitutes invasive mechanical procedures with less harmful chemical/biological actions, eliminating the need for general anesthesia and reducing physical trauma to the animal
2Object-affected harmful factors
If transcervical insemination is used to avoid invasive procedures, then tissue damage is reduced, but the method is not effective enough and breeding outcomes are poor
Solution Approach 1:
The patent applies preliminary action by treating the cervix with ripening agents (prostaglandins, papaya latex, or other natural substances) before attempting transcervical insemination. This preliminary softening and dilation of the cervix makes the transcervical route feasible and effective, allowing insemination catheters to pass through without excessive force while maintaining low tissue damage. The pre-treatment ensures that the cervix is sufficiently prepared to accept the catheter and deliver sperm successfully
Solution Approach 2:
The patent changes the physical parameters of the cervix (softness, elasticity, diameter) through the application of cervical ripening agents. By modifying these parameters temporarily before the procedure, the cervix becomes more compliant and easier to pass through, enabling effective transcervical insemination without requiring invasive surgical intervention, thus achieving both reduced tissue damage and improved breeding success
3Ease of operation
If harsh procedures are used to prepare reproductive tracts, then passage through restricted orifices is achieved, but infection risk and inflammation increase
Solution Approach 1:
The patent replaces harsh mechanical procedures (forceful dilation, surgical incision, laparoscopic manipulation) with a biochemical preparation method using cervical ripening agents. These agents chemically soften and prepare the cervical tissue, allowing instruments to pass through with minimal mechanical trauma. This substitution reduces the risk of tissue damage, bleeding, and subsequent infection that would result from forceful mechanical dilation or surgical intervention
Solution Approach 2:
The patent introduces cervical ripening agents (prostaglandins, papaya latex, or other natural substances) as an intermediary substance that mediates between the need for cervical passage and the risk of tissue damage. This intermediary agent prepares the cervix chemically, creating a favorable environment for instrument passage while minimizing direct mechanical contact and potential for introducing pathogens or causing inflammation. The intermediary treatment reduces infection risk by avoiding the need for forceful, potentially contaminating mechanical dilation
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The method increases breeding success by reducing tissue damage, infection risk, and improving pregnancy rates while avoiding the need for anesthesia and harsh procedures.
Implementation Method 1
A non-sedative, minimally invasive method using a natural substance-based treatment applied topically to relax reproductive tissues
Data Source
AI summary
Embodiments of the application provide methods and systems for the relaxation of target tissues (10) of mammals (1) using a treatment (2) having a natural substance (3). A natural substance may be a plant-based or even an algae-based substance. A treatment may be applied to a target tissue with a treatment applicator (8) and even a delivery mechanism (11). A mammal may be positioned perhaps with an elevation mechanism (13) for exposure of the target tissue to a treatment.