3D/4D CEUS Parameter Control for Real-Time Microbubble Perfusion

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Solution Overview

Problem

Existing 2D real-time CEUS imaging frame rates are insufficient for capturing the complete perfusion process of microbubbles, limiting the ability of doctors to provide reliable diagnoses due to low imaging velocities and limited computing power of current systems.

Innovation Solution

A 3D/4D CEUS imaging apparatus and method that allows for selectable contrast imaging modes and velocities, with adjustable imaging parameters such as number of transmissions, line density, and region of interest (ROI) to enhance imaging speed and data processing capabilities.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If 3D/4D contrast-enhanced imaging is performed with high imaging velocity, then real-time observation capability is improved, but the amount of data processing required increases beyond system capabilities

Engineering Contradiction:
Improveimaging velocityVSAvoiddata processing capability
Core Design Contradiction:
SpeedVSDevice complexity

Solution Approach 1:

The patent segments the imaging process into multiple adjustable parameters including number of transmissions, line density, and region of interest (ROI) settings. By dividing the overall imaging task into controllable components, the system can process data at high velocities without overwhelming the computing system, as each parameter can be independently optimized to balance speed and processing load.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements dynamic adjustment of imaging parameters based on real-time system performance and clinical needs. The imaging velocity and related parameters (transmissions, line density, ROI) are made dynamically configurable, allowing the system to adapt processing demands to match both the imaging speed requirements and the actual data processing capabilities of the system.

Inventive Principle:
Principle #15Dynamics

2Speed

If imaging parameters are adjusted to increase imaging velocity, then real-time observation is improved, but image quality or data completeness may deteriorate

Engineering Contradiction:
Improveimaging velocityVSAvoidimage quality
Core Design Contradiction:
SpeedVSManufacturing precision

Solution Approach 1:

The patent systematically varies multiple imaging parameters (number of transmissions, line density, ROI range) to achieve different imaging velocities while maintaining acceptable image quality. By changing these parameters in coordinated ways, the system can select optimal settings that balance imaging speed with the completeness and quality of the acquired data for reliable diagnosis.

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If the number of transmissions and line density are increased to improve image quality, then data processing load increases, but imaging velocity decreases

Engineering Contradiction:
Improveimage qualityVSAvoidimaging velocity
Core Design Contradiction:
Manufacturing precisionVSSpeed

Solution Approach 1:

The patent applies partial action by allowing users to select ROI (region of interest) that focuses processing resources on only the necessary portions of the imaging volume. Instead of processing entire volumes at maximum detail, the system processes only the relevant regions with appropriate transmission and line density settings, thereby maintaining image quality in critical areas while reducing overall processing load and improving effective imaging velocity.

Inventive Principle:
Principle #16Partial or excessive action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables real-time observation and reliable diagnosis by capturing the complete perfusion process of microbubbles, particularly in small lesions with hypervascularity, using a planar array probe with electronic stereo scanning to improve imaging velocity and data processing efficiency.

Implementation Method 1

a transmitting circuit configured to excite the planar array probe to transmit ultrasonic waves to a target, a receiving circuit configured to control the planar array probe to receive ultrasonic echo signals from the target

Methodology Applied
Scientific EffectUltrasonic wave transmission and echo reception: Ultrasound

Implementation Method 2

receiving an input for selecting a 3D contrast-enhanced imaging mode or a 4D contrast-enhanced imaging mode; receiving an input for setting an imaging velocity; and controlling the 3D/4D contrast-enhanced ultrasound imaging apparatus with an imaging parameter associated with the selected contrast-enhanced imaging mode and the set imaging velocity

Methodology Applied
Scientific EffectContrast-enhanced ultrasound imaging: Ultrasound

Data Source

PatentUS12478354B23D/4D contrast-enhanced ultrasound imaging apparatus, methods and media
Publication Date: 2025.11.25 SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
  • US12478354B2 patent drawing
  • US12478354B2 patent drawing
  • US12478354B2 patent drawing

AI summary

Disclosed are 3D/4D contrast-enhanced ultrasound imaging (CEUS) apparatus, 3D/4D CEUS imaging methods and media. The method comprises: receiving an input for selecting a 3D/4D contrast-enhanced imaging mode; receiving an input for setting an imaging velocity including a first imaging velocity and a higher second imaging velocity; controlling the apparatus with an imaging parameter associated with the selected imaging mode and the set imaging velocity to achieve imaging with the selected imaging mode in the set imaging velocity, wherein an association between the imaging parameter and the imaging velocity allows that an amount of data required to generate images per volume using the first imaging velocity is greater than that using the second imaging velocity. In this way, a desired imaging mode and imaging velocity can be chosen freely and an imaging parameter can be selected pointedly, meeting real-time observation needed by doctors with limited data processing capability and various probes.