CH010376 Hybrid Corn Breeding for Uniform Traits and Yield

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Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and stability, combining desirable traits such as yield, disease resistance, and drought tolerance, while maintaining genetic purity and preventing self-pollination.

Innovation Solution

The development of the hybrid corn variety CH010376, which includes genetic modifications for traits like male sterility, herbicide resistance, and disease resistance, achieved through cytoplasmic and nuclear factors, and utilizes methods like backcrossing and genetic transformation to introduce specific alleles and transgenes, ensuring uniformity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If conventional breeding techniques are used to develop corn hybrids, then genetic diversity can be maintained, but uniformity and stability of desirable traits such as yield, disease resistance, and drought tolerance are difficult to achieve

Engineering Contradiction:
Improveuniformity and stability of desirable traitsVSAvoidyield
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The breeding program segments the development process into distinct phases: creating homozygous inbred lines through multiple generations of self-pollination, then crossing these standardized lines to produce uniform F1 hybrids. This segmentation allows each phase to be optimized independently, ensuring both uniformity in the final product and high yield potential.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies preliminary action by extensively pre-selecting and stabilizing parental inbred lines through multiple generations of self-pollination and selection before crossing. This preliminary stabilization of genetic composition in the parental lines ensures that the resulting F1 hybrids exhibit consistent uniformity and stability of desirable traits while maintaining high yield potential.

Inventive Principle:
Principle #10Preliminary action

2Reliability

If self-pollination is allowed in corn plants, then genetic purity of inbred lines can be maintained, but cross-pollination is necessary to produce hybrid vigor and superior performance

Engineering Contradiction:
Improvegenetic purityVSAvoidhybrid vigor
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The breeding system segments the reproductive process into two distinct phases: Phase 1 uses self-pollination to maintain genetic purity and homozygosity in parental inbred lines, while Phase 2 uses controlled cross-pollination between different inbred lines to generate hybrid vigor in F1 progeny. This segmentation resolves the contradiction by applying the appropriate pollination method to each breeding objective.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses spatial isolation and temporal scheduling as intermediary mechanisms to control pollination. Physical barriers and distance separation prevent unwanted cross-pollination during the inbreeding phase, while controlled removal of these barriers enables desired cross-pollination during the hybridization phase, thus maintaining genetic purity when needed and enabling hybrid vigor when required.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If multiple desirable traits are combined in a single hybrid, then overall performance and adaptability improve, but the complexity of breeding programs and selection processes increases

Engineering Contradiction:
ImproveadaptabilityVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The breeding program segments trait incorporation into separate parental lines, each optimized for specific traits (e.g., one parent for disease resistance, another for drought tolerance). By dividing the complex multi-trait objective into manageable parental components, the program reduces selection complexity while achieving comprehensive adaptability in the final hybrid through complementary gene action.

Inventive Principle:
Principle #1Segmentation

4Reliability

If extensive selection and evaluation of inbred plants is performed, then superior hybrids can be developed, but the time required to bring new varieties to market increases

Engineering Contradiction:
Improvesuperior hybrid qualityVSAvoidtime to maturity
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by conducting extensive selection and stabilization of parental inbred lines in advance, across multiple generations, before the hybridization phase. This upfront investment of time in creating genetically stable, superior parental lines reduces the need for extensive subsequent evaluation, as the F1 hybrids inherit predictable, optimized traits from well-characterized parents, thus improving quality while managing overall development time.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12457960B2Plants and seeds of hybrid corn variety CH010376
Publication Date: 2025.11.04 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH010376. The invention thus relates to the plants, seeds and tissue cultures of the variety CH010376, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010376 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH010376.