Hybrid Corn Variety CH010449 for Stable Multi-Trait Breeding

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Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and stability, incorporating desirable traits such as yield, disease resistance, and genetic modifications efficiently.

Innovation Solution

The development of the hybrid corn variety CH010449, which includes cytoplasmic and nuclear factors for male sterility, genetic loci for traits like herbicide resistance and disease resistance, and the use of genome editing techniques to introduce specific alleles, along with a method for controlled cross-pollination to ensure hybrid purity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If traditional breeding methods are used to develop corn hybrids, then genetic diversity is maintained, but uniformity and stability of the hybrid population are compromised

Engineering Contradiction:
Improvehybrid uniformityVSAvoidbreeding process complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The breeding process is segmented into distinct phases: developing male-sterile lines for controlled pollination, creating F1 hybrids with uniform traits, and maintaining genetic diversity through structured population management. This segmentation enables simultaneous achievement of hybrid uniformity and genetic diversity

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Male-sterile lines serve as intermediaries to ensure controlled cross-pollination without self-fertilization. These lines act as mediators that guarantee hybrid purity and uniformity while maintaining systematic breeding processes

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If multiple desirable traits are incorporated into a single hybrid, then agronomic performance is improved, but breeding time and resource requirements increase

Engineering Contradiction:
Improveagronomic performanceVSAvoidbreeding development time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

Desirable traits such as disease resistance, herbicide tolerance, and yield components are pre-selected and incorporated into parental lines before hybrid creation. This preliminary action allows multiple traits to be combined in a single breeding cycle rather than requiring sequential trait addition

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The breeding system is designed to handle multiple traits simultaneously through universal selection criteria and integrated evaluation protocols. Parental lines are developed with multiple desired characteristics, enabling the F1 hybrid to inherit and express multiple agronomically important traits together

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Stability of the object's composition

If strict control measures are implemented to ensure hybrid purity, then genetic uniformity is maintained, but production costs increase

Engineering Contradiction:
Improvehybrid purityVSAvoidproduction cost
Core Design Contradiction:
Stability of the object's compositionVSEase of manufacture

Solution Approach 1:

Male-sterile lines automatically prevent self-fertilization and ensure cross-pollination without requiring manual emasculation or intensive monitoring. The biological characteristic of male sterility serves the breeding program by self-enforcing hybrid purity controls

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

Male-sterile lines act as intermediaries that biologically enforce controlled pollination. Their inherent inability to self-fertilize serves as a natural control mechanism that maintains hybrid purity while reducing the need for expensive manual intervention and monitoring infrastructure

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS12588616B2Plants and seeds of hybrid corn variety CH010449
Publication Date: 2026.03.31 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010449. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010449, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010449 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010449.