Hybrid Corn Variety CH010516 Breeding for Uniform Seed Purity

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and desirable traits such as yield, disease resistance, and drought tolerance, while maintaining genetic stability and commercial viability.

Innovation Solution

The development of the hybrid corn variety CH010516, which incorporates cytoplasmic and nuclear factors for male sterility, genetic modifications for traits like herbicide resistance and disease resistance, and a method of controlled cross-pollination to ensure uniformity and desirable characteristics, along with the use of genome editing techniques for precise genetic locus modifications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If conventional breeding techniques are used to develop corn hybrids, then genetic diversity can be maintained, but achieving uniformity in germination, growth, and desirable traits becomes difficult

Engineering Contradiction:
Improveuniformity in germination and growthVSAvoidbreeding process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The breeding process is segmented into distinct stages: developing homozygous inbred parental lines through multiple generations of self-pollination, then crossing these standardized parents to produce uniform F1 hybrids. This segmentation allows each stage to be optimized independently, achieving uniformity through controlled inbreeding followed by hybridization.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs cytoplasmic male sterility (CMS) as a genetic parameter change to prevent self-pollination in the hybrid generation. By introducing specific cytoplasmic factors that confer male sterility, the system ensures uniform cross-pollination occurs, eliminating variability from selfing and achieving consistent hybrid uniformity.

Inventive Principle:
Principle #35Parameter changes

2Stability of the object's composition

If self-pollination is used to develop homozygous inbred lines, then genetic stability is achieved, but the time required to develop stable varieties increases

Engineering Contradiction:
Improvegenetic stability of inbred linesVSAvoidtime to develop stable varieties
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

Homozygous inbred parental lines are developed in advance through multiple generations of self-pollination and selection before the hybridization step. This preliminary action ensures genetic stability is established beforehand, allowing the subsequent hybrid generation to uniformly express desirable traits without requiring additional time for stabilization.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Once stable inbred lines are established, they serve as standardized parental copies that can be repeatedly crossed to produce uniform hybrid progeny. The homozygous parental lines act as genetic templates, ensuring consistent transmission of desired traits across multiple hybrid production cycles without requiring re-development of the parental genetics.

Inventive Principle:
Principle #26Copying

3Adaptability or versatility

If cross-pollination is used to produce hybrid varieties, then desirable traits from different parents are combined, but preventing self-pollination and maintaining hybrid purity becomes challenging

Engineering Contradiction:
Improvecombination of desirable traitsVSAvoidhybrid seed purity
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

Cytoplasmic male sterility acts as an intermediary mechanism to prevent self-pollination in hybrid production. The CMS cytoplasm in the female parent creates a biological barrier that eliminates viable pollen, ensuring that only cross-pollinated seeds are produced. This intermediary system reliably maintains hybrid purity while allowing combination of desirable traits from both parents.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent extracts and removes the self-pollination capability from the hybrid production system by introducing cytoplasmic factors that confer male sterility. By taking out the ability to self-pollinate, the system ensures that only controlled cross-pollination occurs, maintaining hybrid seed purity while still achieving combination of desirable traits through deliberate parental crosses.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS12616129B2Plants and seeds of hybrid corn variety CH010516
Publication Date: 2026.05.05 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010516. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010516, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010516 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010516.