Chain Composition Apparatus for Precise Drug Infusion Control

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Solution Overview

Problem

Current transcatheter arterial infusion therapy for cancer treatment faces challenges in consistently controlling drug infusion pressure and speed, leading to potential drug reflux or inadequate tumor penetration due to operator-dependent adjustments.

Innovation Solution

A chain composition preparation apparatus and method that uses a distribution valve with multiple ports, syringes, and connecting tubes to alternately aspirate and inject different media, forming a chain-like composition for precise drug delivery, enabling on-site preparation and administration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual adjustment of pressure and speed through repeated imaging is used, then operator flexibility is maintained, but consistency and precision of drug infusion are compromised due to subjective biases

Engineering Contradiction:
Improveprecision of drug infusionVSAvoidcomplexity of infusion control system
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces manual mechanical adjustment with an automated control system that uses sensors to detect catheter position and automatically adjusts infusion pressure and speed, eliminating operator subjective bias while maintaining system simplicity through automated feedback control

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements a feedback mechanism where sensors continuously monitor catheter position and infusion parameters, and the control system automatically adjusts drug delivery based on real-time feedback to maintain precise and consistent infusion conditions

Inventive Principle:
Principle #23Feedback

2Productivity

If high pressure or speed is used for drug infusion, then drug delivery efficiency is improved, but risk of drug reflux or microcatheter expulsion increases

Engineering Contradiction:
Improvedrug delivery efficiencyVSAvoidrisk of drug reflux or catheter expulsion
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent employs dynamic adjustment of infusion pressure and speed based on real-time catheter position detection, automatically optimizing delivery efficiency while preventing harmful effects by adapting parameters to current operational conditions

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent preemptively adjusts infusion parameters before problematic conditions occur by continuously monitoring catheter position and predicting potential issues, preventing drug reflux or catheter expulsion before they happen

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

3Reliability

If low pressure or speed is used for drug infusion, then safety is improved by preventing reflux and catheter expulsion, but drug cannot effectively reach tumor interior

Engineering Contradiction:
Improvesafety of infusionVSAvoideffectiveness of tumor penetration
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent dynamically adjusts infusion parameters based on real-time feedback from sensors, automatically optimizing the balance between safety and effectiveness by adapting pressure and speed to current catheter position and treatment requirements

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS20240269381A1Chain composition preparation apparatus and preparation method
Publication Date: 2024.08.15 MEDESSENCE LIFESCIENCES SUZHOU INC
  • US20240269381A1 patent drawing
  • US20240269381A1 patent drawing
  • US20240269381A1 patent drawing

AI summary

Disclosed is a chain composition preparation apparatus, comprising a filling part, an injection part, a first connecting tube, a second connecting tube, a distribution valve and an outlet fluid tube. The filling part is in communication with the injection part via the first connecting tube, the distribution valve is in communication with the first connecting tube via the second connecting tube, and the outlet fluid tube is connected to the distribution valve; the distribution valve is also used to connect to an external gas supply part and a liquid supply part. The filling part is used to suck gas and liquid to sequentially enter the second connecting tube, to form a drug in an alternating gas-liquid dosage form. Thus, integration of drug configuration and drug injection can be achieved, so that convenience and efficiency of drug injection is improved.