Charged Particle Extraction via Foil Energy Reduction

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Solution Overview

Problem

Current charged particle irradiation therapy systems face challenges in accurately and precisely delivering a uniform radiation dose to tumors while minimizing damage to surrounding healthy tissue, requiring improved patient positioning, imaging, and control over radiation distribution.

Innovation Solution

A charged particle beam therapy system that utilizes a synchrotron with a negative ion beam source, RF cavity for betatron oscillation, and advanced magnetic field control to extract and focus protons, combined with patient positioning and imaging systems for precise tumor targeting and radiation delivery.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If charged particle beam therapy is used to treat tumors, then tumor treatment effectiveness is improved, but damage to surrounding healthy tissue increases

Engineering Contradiction:
Improvetumor treatment effectivenessVSAvoiddamage to surrounding healthy tissue
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by delivering charged particle beams to specific tumor locations while sparing surrounding healthy tissue. The system uses imaging guidance and positioning systems to target the beam precisely at the tumor site, allowing high radiation dose to the tumor while minimizing exposure to adjacent healthy structures.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent replaces conventional mechanical positioning methods with advanced imaging systems and computer-controlled positioning. The imaging system provides real-time feedback to adjust beam placement, replacing manual mechanical alignment with automated image-guided targeting for improved precision.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If precise tumor targeting is achieved through imaging and positioning systems, then radiation delivery accuracy is improved, but device complexity increases

Engineering Contradiction:
Improveradiation delivery accuracyVSAvoidimaging and positioning system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent implements multi-functionality by integrating imaging, positioning, and beam delivery control into a single coordinated system. The imaging system serves multiple purposes: tumor localization, beam alignment verification, and treatment monitoring, reducing the need for separate systems and simplifying the overall architecture.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent employs feedback mechanisms where the imaging system continuously monitors beam placement and provides real-time information to the control system. This feedback loop allows automatic adjustment of beam positioning to maintain high accuracy despite variations in patient positioning or tissue movement.

Inventive Principle:
Principle #23Feedback

3Manufacturing precision

If charged particle beam parameters (energy, intensity, timing) are controlled for precise radiation distribution, then tumor treatment precision is improved, but control system complexity increases

Engineering Contradiction:
Improveradiation distribution precisionVSAvoidcontrol system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies dynamics by making beam parameters adjustable and adaptable rather than fixed. The control system can dynamically modify energy, intensity, and timing parameters in real-time based on treatment requirements and patient response, allowing precise control for different tumor types and stages without requiring completely separate systems for each parameter.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent merges control of multiple beam parameters (energy, intensity, timing) into a single integrated control system that coordinates all parameters simultaneously. This unified approach ensures precise radiation distribution by optimizing the interaction between parameters rather than controlling them independently, reducing overall system complexity.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables efficient, accurate, and precise non-invasive tumor treatment with reduced tissue damage by controlling proton beam energy, intensity, and timing, ensuring effective radiation distribution to tumors while minimizing exposure to healthy tissue.

Implementation Method 1

a synchrotron with a negative ion beam source, RF cavity for betatron oscillation

Methodology Applied
Scientific EffectElectromagnetic acceleration: Electromagnetic Induction

Implementation Method 2

RF cavity for betatron oscillation

Methodology Applied
Scientific EffectBetatron oscillation:

Implementation Method 3

advanced magnetic field control to extract and focus protons

Methodology Applied
Scientific EffectMagnetic field focusing: Magnetic Field

Implementation Method 4

aiming energetic ionizing particles, such as protons accelerated with a particle accelerator, onto a target tumor. These particles damage the DNA of cells

Methodology Applied
Scientific EffectIonizing radiation: Radiation

Data Source

PatentUS8399866B2Charged particle extraction apparatus and method of use thereof
Publication Date: 2013.03.19 BALAKIN ANDREY VLADIMIROVICH
  • US8399866B2 patent drawing
  • US8399866B2 patent drawing
  • US8399866B2 patent drawing

AI summary

The invention comprises a charged particle beam extraction method and apparatus optionally used in conjunction with charged particle beam radiation therapy of cancerous tumors. The system uses a radio-frequency (RF) cavity system to induce oscillation of a charged particle stream. Sufficient amplitude modulation of the charged particle stream causes the charged particle stream to hit a material, such as a foil element of a set of foils. The foil decreases the energy of the charged particle stream, which decreases a radius of curvature of the charged particle stream in the synchrotron sufficiently to allow a physical separation of the reduced energy charged particle stream from the original charged particle stream where thickness of a selected foil is a function of energy of circulating charged particles. The physically separated charged particle stream is then removed from the system by use of an applied field and deflector.