Chelated Copper Chlorin Composition for Hair Density and Diameter
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Solution Overview
Problem
There is a need for safe and effective topically applied compositions to increase both the number and diameter of terminal hairs, addressing hair thinning due to disease, genetics, chemical exposure, nutrition, environmental stressors, and aging.
Innovation Solution
A topical hair volumizing composition containing a chelated copper chlorin compound, primarily composed of trisodium copper (II) chlorin e6 or disodium copper (II) isochlorin e4, is applied to the skin or scalp to increase hair density and diameter.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If conventional topically applied compositions are used, then hair density may be maintained, but the ability to increase both the number and diameter of terminal hairs is insufficient
Solution Approach 1:
The patent changes the chemical parameters of the topical composition by using chelated copper chlorin compounds (specifically trisodium copper (II) chlorin e6 and disodium copper (II) isochlorin e4) at optimized concentrations of 0.01-0.5% w/w. This parameter change enables the composition to effectively increase both the number and diameter of terminal hairs, resolving the contradiction between maintaining hair density and achieving terminal hair growth effectiveness.
2Quantity of substance
If higher concentrations of active ingredients are used to increase hair density, then terminal hair growth improves, but the safety and tolerability of the composition decreases
Solution Approach 1:
The patent optimizes the concentration parameter of the chelated copper chlorin compound to a specific range of 0.01-0.5% w/w, which has been determined to be the effective and safe concentration range. This parameter optimization allows the composition to increase terminal hair density while maintaining skin safety and tolerability, avoiding the harmful effects associated with higher concentrations.
Solution Approach 2:
The chelated copper chlorin compound acts as an intermediary substance that mediates between the desired effect of increasing hair density and the potential harmful effects of high concentration. The chelated form of copper chlorin provides biological activity at low concentrations, serving as an effective mediator that achieves therapeutic effects without causing skin irritation.
3Productivity
If multiple active ingredients are combined to achieve comprehensive hair density improvement, then treatment effectiveness increases, but the composition complexity and manufacturing difficulty increase
Solution Approach 1:
The patent extracts and isolates the key active ingredient (chelated copper chlorin compound) from complex hair care formulations, demonstrating that a single well-selected ingredient can achieve comprehensive hair density improvement. This extraction simplifies the composition formulation while maintaining high treatment effectiveness, reducing both formulation complexity and manufacturing difficulty.
Data Source
AI summary
Methods for increasing the density and diameter of human hair comprised of the step of applying to any skin area of the body and/or the scalp covered with hair, a topical hair volumizing composition comprised of a chelated copper chlorin compound, wherein the chelated copper chlorin compound is comprised of at least 75% of a chlorin species selected from the group consisting of trisodium copper (II) chlorin e6 and disodium copper (II) isochlorin e4, and the chelated copper chlorin compound is present at a concentration of from 0.02 to 0.1% by weight of the composition.