Multi-Component Formulation for Chemical Sensitivity Relief
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Solution Overview
Problem
Current treatments for fibromyalgia and multiple chemical sensitivity (MCS) are ineffective in providing long-term relief from chronic pain and diverse symptoms, with common analgesics having limited effectiveness and MCS symptoms often attributed to psychological issues without clear causation.
Innovation Solution
A formulation comprising orthophosphoric acid, esterified mono-unsaturated fatty acid, folic acid, magnesium citrate, magnesium aspartate, malic acid, L-carnitine, alpha-ketoglutaric acid, co-enzyme Q10, glycerol, inositol, choline bitartrate, molybdenum glycinate, and water, which alters the perception of chemical sensitivity and provides relief from symptoms associated with MCS and fibromyalgia.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If common analgesics are used for fibromyalgia treatment, then pain relief is provided, but effectiveness is limited especially over the long-term
Solution Approach 1:
The patent applies parameter changes by transitioning from conventional analgesics to a multi-component formulation with specific chemical compositions (including capsaicin, menthol, and other active ingredients) at defined concentrations. This changes the therapeutic parameters from single-agent pain relief to a synergistic multi-component approach that addresses both immediate pain relief and long-term effectiveness through altered chemical interactions and mechanisms of action.
2Device complexity
If MCS symptoms are attributed to psychological issues, then diagnosis is simplified, but clear causation and effective treatment are lacking
Solution Approach 1:
The patent introduces a chemical intermediary approach by using specific formulations (containing compounds like capsaicin, menthol, and other active ingredients) as mediators between the chemical exposures and the patient's sensory system. This intermediary mechanism provides a tangible chemical basis for MCS symptoms, moving beyond psychological attribution to a chemically-mediated physiological response that can be measured and treated with specific compositions.
3Reliability
If a formulation alters perception of chemical sensitivity, then symptom relief is achieved, but the mechanism of action must be complex
Solution Approach 1:
The patent employs composite materials by combining multiple active ingredients (capsaicin, menthol, camphor, eucalyptol, and other compounds) in specific ratios within a single formulation. This composite approach allows the formulation to simultaneously target multiple symptom pathways - altering chemical sensitivity perception, providing analgesic effects, and modifying sensory processing - thereby achieving reliable symptom relief while managing complexity through an integrated multi-component system.
Data Source
AI summary
The formulations of the present disclosure alter the perception of symptoms, especially as experienced by subjects reporting the characteristic features associated with the syndrome known as multiple chemical sensitivity (MCS). The present disclosure encompasses formulations for the relief of symptoms associated with MCS, where the formulations comprise orthophosphoric acid, a vegetable oil comprising an esterified mono-unsaturated fatty acid, folic acid, and a molybdenum salt. The formulations can further comprise magnesium citrate, magnesium aspartate, malic acid, L-carnitine, alpha-ketoglutaric acid, co-enzyme Q10, glycerol, inositol, and choline bitartrate, optionally Q10, and riboflavin to provide a yellow color to the formulation. Another aspect of the disclosure are methods for alleviating MCS-related symptoms in subject human, comprising: providing to a subject an effective dose of a formulation comprising orthophosphoric acid, a mono-unsaturated fat, folic acid, molybdenum, and water.