Chemical Shift Corrected Calibration Maps for Parallel MRI

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Solution Overview

Problem

Conventional fat suppression methods in MRI, such as STIR and spectral-spatial pulses, fail to provide reliable and uniform fat suppression in areas with magnetic field heterogeneities, leading to reduced signal-to-noise ratio and limited T1 weighted applications, especially in extremity and off-isocenter imaging.

Innovation Solution

A method involving the acquisition of multiple echoes at different echo times to create a chemical shift corrected calibration map, using IDEAL (Iterative Decomposition with Echo Asymmetry and Least Squares Estimation) to separate water and fat signals and correct for chemical shift artifacts, enabling improved sensitivity calibration and parallel imaging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fat suppression methods (STIR, spectral-spatial pulses) are used, then fat suppression is achieved, but signal-to-noise ratio is reduced and T1 weighted applications are limited

Engineering Contradiction:
Improvefat suppression reliabilityVSAvoidsignal-to-noise ratio
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent segments the water and fat signals by acquiring multiple echoes at different echo times, allowing separate processing and combination of water and fat components. This segmentation enables reliable fat suppression while preserving the water signal quality, resolving the contradiction between fat suppression reliability and signal-to-noise ratio.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent adds the time dimension by acquiring multiple echoes at different echo times (TE). This temporal dimension allows the system to separate water and fat signals based on their different chemical shifts, achieving reliable fat suppression without degrading the signal-to-noise ratio of the water image.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Productivity

If parallel imaging is used to increase scanning speed, then productivity is improved, but calibration map accuracy is degraded due to chemical shift artifacts

Engineering Contradiction:
Improvescanning speedVSAvoidcalibration map accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent performs preliminary water-fat separation and chemical shift correction on the calibration data before using it for parallel imaging reconstruction. By pre-processing the calibration maps to remove chemical shift artifacts, the system maintains high calibration accuracy while still benefiting from the speed improvements of parallel imaging.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses acquired echoes to generate calibration maps, which are then used to improve the accuracy of subsequent parallel imaging reconstructions. This feedback loop ensures that chemical shift artifacts are systematically corrected, maintaining calibration map accuracy while enabling fast parallel imaging.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If multiple echoes at different echo times are acquired to create chemical shift corrected calibration map, then calibration accuracy is improved, but scanning time is increased

Engineering Contradiction:
Improvecalibration map accuracyVSAvoidscanning time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent changes the echo time parameter across multiple acquisitions to exploit the different chemical shifts of water and fat. By strategically selecting echo times, the system achieves accurate water-fat separation and chemical shift correction. When combined with parallel imaging, this parameter variation achieves high calibration accuracy without excessive time penalty.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the signal-to-noise ratio and allows for accurate fat suppression across various imaging applications, including T1 weighted imaging, by eliminating chemical shift artifacts and improving imaging efficiency at higher field strengths without increasing bandwidth.

Implementation Method 1

exploit the difference in chemical shifts between water and fat and in order to separate water and fat into separate images

Methodology Applied
Scientific EffectChemical shift:

Data Source

PatentUS7741842B2Calibration maps for parallel imaging free of chemical shift artifact
Publication Date: 2010.06.22 GENERAL ELECTRIC CO
  • US7741842B2 patent drawing
  • US7741842B2 patent drawing
  • US7741842B2 patent drawing

AI summary

A method for generating a calibrated parallel magnetic resonance image is provided in a manifestation of the invention. A magnetic resonance imaging excitation is applied. A plurality of echoes at different echo times (TE) is acquired. The acquired plurality of echoes from different echo times is used to create a chemical shift corrected calibration map.