Portable Chemical Testing Assembly for Rapid Toxic Industrial Chemical Detection

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Solution Overview

Problem

Current methods for detecting toxic industrial chemical (TIC) exposure, such as cyanide, hydrogen sulfide, and ammonia, are slow and often require laboratory analysis, leading to delayed diagnosis and inadequate response times due to the need for biological samples and complex testing procedures.

Innovation Solution

A portable testing assembly comprising a sample collection device, a chemical capture cartridge, and a sensing device that isolates and detects TICs within minutes, using reagents and a sensing mechanism to provide rapid onsite analysis of chemical exposure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If laboratory analysis methods are used for TIC detection, then measurement precision is improved, but loss of time increases significantly

Engineering Contradiction:
Improvedetection accuracyVSAvoiddiagnosis time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The testing assembly is divided into distinct functional modules: a sample collection device with capillary tube for blood sampling, a chemical capture cartridge with separate chambers for sample introduction and chemical capture, and a sensing device. This segmentation allows each component to perform its function efficiently and enables rapid sequential processing of the sample through each stage.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The chemical capture cartridge is pre-loaded with reagents and capture media before sample introduction. The system is prepared in advance with all necessary chemicals and configurations, eliminating setup time during actual testing and enabling immediate analysis upon sample collection.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If complex testing procedures are used, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvedetection accuracyVSAvoidtesting procedure complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

Multiple functions are merged into a single integrated cartridge: sample reception, chemical capture, reagent mixing, and detection all occur within one chemical capture cartridge. This consolidation simplifies the overall device architecture and reduces the number of separate components and操作步骤 required.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The system performs automated sample processing through capillary action and pre-configured chemical reactions. The capillary tube automatically draws blood samples, and the reagents in the cartridge automatically react with the sample without requiring manual intervention, mixing, or complex operational steps by the user.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If biological samples are required for analysis, then measurement precision is improved, but ease of operation deteriorates

Engineering Contradiction:
Improvedetection accuracyVSAvoidsample collection difficulty
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The testing assembly uses a disposable capillary tube for sample collection and a single-use chemical capture cartridge. These disposable components eliminate the need for cleaning, sterilization, and complex sample collection procedures, making the device easy to operate while maintaining detection accuracy through dedicated single-use design.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

4Loss of time

If rapid detection is implemented, then loss of time is reduced, but measurement precision may deteriorate

Engineering Contradiction:
Improvedetection timeVSAvoiddetection accuracy
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The system uses specific chemical reagents and capture media with optimized properties for rapid binding and detection of target chemicals. The chemical reactions are designed to proceed quickly while maintaining specificity, and the sensing device parameters are optimized for fast signal generation without sacrificing detection accuracy.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables rapid detection of TICs in 2 minutes or less, facilitating timely response and action in emergency situations by providing a portable, efficient, and cost-effective means for onsite chemical exposure diagnosis.

Implementation Method 1

The sample chamber configured to react the sample with at least the first liquid reagent to provide a headspace gas having the desired chemical analyte

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Implementation Method 2

the capture chamber of the chemical capture cartridge is configured to react the desired chemical analyte with at least the second liquid reagent to provide a desired detectable complex

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Implementation Method 3

the sensing device is capable of providing a signal indicating the presence or absence of the desired chemical analyte

Methodology Applied
Scientific EffectSensing detection:

Data Source

PatentUS11285480B1Rapid chemical testing assembly and methods thereof
Publication Date: 2022.03.29 ANALYTICAL & DIAGNOSTIC SOLUTIONS LLC
  • US11285480B1 patent drawing
  • US11285480B1 patent drawing
  • US11285480B1 patent drawing

AI summary

A testing assembly for the rapid detection of a desired chemical from a sample, the testing assembly having a sample collection device for obtaining the sample and depositing the sample into a chemical capture cartridge that operably engages with a sensing device, the chemical capture cartridge utilizing the microdiffusion of reagents to isolate the desired chemical from the sample and react the desired chemical to form a detectible complex that can be detected and measured. The testing assembly can be portable and can rapidly diagnose a toxic industrial chemical exposure in just a few minutes, preferably about a minute or less for cyanide exposure using a blood sample from a subject onsite. The testing assembly can be used to determine the presence and/or concentration of a toxic industrial chemical in a variety of samples, including biological, environmental, and industrial samples.